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Metabolomics1H NMR metabolomic and transcriptomic analyses reveal urinary metabolites as biomarker candidates in response to protein undernutrition in adult rats

BACKGROUND: Protein undernutrition is prevalent mainly among elderly people, and it could develop diseases such as sarcopenia. Urinary metabolites may become biomarkers reflecting protein undernutrition, but this has been insufficiently investigated.

OBJECTIVE:

2021-05-27 | MTBLS1452 | MetaboLights
ProteomicsIdentification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma - LC-MS Part
The aim of this study was the identification of biomarkers for the immunohistochemical diagnosis of cholangiocellular carcinoma (CCC). CCC is a primary cancer which arises from the epithelial cells of the bile ducts and is characterised by high mortality rates due to its late clinical presentation a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082885 | MassIVE
GenomicsmiRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
miRNA profiling of putative biomarker candidates in Mycobacterium avium subsp. paratuberculosis-infected cattle
PRJNA699634 | ENA
TranscriptomicsTranscription profiling of human quadriceps femoris muscle following statin treatment to identify potential biomarker candidates related to statin-induced changes in muscle metabolism
The experiment is part of a study using systems biology approach to analyze muscle gene expression and UPLC-MS based plasma lipidomics profiling data to illuminate relevant biological pathways and to find potential biomarker candidates related to statin-induced changes in muscle metabolism.
ORGANISM(S): Homo sapiens 
2007-03-01 | E-TABM-116 | biostudies-arrayexpress
ProteomicsLow-Abundance Serum Protein Biomarker Candidates for HCC in Patients with Liver Cirrhosis
In this study, we employed both untargeted and targeted analysis of low abundance serum proteins to identify potential biomarkers for HCC. We employed a two-phase proteomics approach to identify low abundance serum proteins as potential biomarkers for HCC.The first phase involved DDA-based untargete...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD061721 | Pride
Nano-lc-ms/ms Low abundance protein Serum Liliver cancer Biomarker 
ProteomicsThe identification of onchocerciasis biomarker candidates directly in human serum and urine
Onchocerca volvulus, the causative agent of onchocerciasis, infects over 20 million people and can cause severe dermatitis and ocular conditions including blindness. Current mass drug administration treatments do not kill female O. volvulus worms, and common diagnostic tests cannot reliably assess t...
ORGANISM(S): Homo Sapiens Onchocerca Volvulus 
2022-11-22 | PXD033659 |
ProteomicsDiscovery of biomarker candidates associated with the risk of short- and long-term relapse after infliximab withdrawal in Crohn’s patients: a proteomics-based study
Objective: A subset of Crohn’s disease (CD) patients experiences long-term remission after infliximab withdrawal. Biomarkers are needed to identify those patients. Design: New biomarkers of relapse were searched in the baseline serum of CD patients stopping infliximab when they were under combined t...
ORGANISM(S): Homo Sapiens 
2020-11-02 | PXD019434 | panorama
OtherDiscovery of colorectal cancer biomarker candidates by membrane proteomic analysisand subsequent verification using selected reaction monitoring and tissue microarrayanalysis
Data from ProteomeXchange, PXD ID: PXD000851. File: iTRAQ3.msf.mgf. Published as part of Mol Cell Proteomics. 2014 Mar 31 . From the Abstract: {{i}} We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then ext...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210027051 | GPMDB
Resource Reanalysis 
GenomicsNon-lethal scute transcriptomics reveals biomarker candidates for environmental stress in Mexican Morelet’s crocodiles
Non-lethal scute transcriptomics reveals biomarker candidates for environmental stress in Mexican Morelet’s crocodiles
PRJNA1406241 | ENA
ProteomicsLabel-free Proteomics for Discovering Biomarker Candidates for Controlling Krypton Misuse in Castrated Horses (Geldings)
Recent advances in label-free quantitative proteomics may support its application in identifying and monitoring biomarkers for the purpose of doping control in equine sports. In this study, we developed a workflow of label-free quantitative proteomics to propose plasma protein biomarkers in horses ...
ORGANISM(S): Equus caballus (Horse) 
2020-02-20 | PXD017262 | Pride
Krypton Proteomics Horse Biomarkers Data-independent acquisition 
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