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Morphology together with the capability to respond to surrounding stimuli are the key elements governing the spatial interaction of a living cell with the environment. In this respect, biomechanical stimulation can trigger significant physiological cascades that can potentially modulate or interact ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD008996 | Pride
The extracellular matrix (ECM) of the ocular trabecular meshwork (TM) builds resistance to aqueous humor outflow, thereby regulating intraocular pressure (IOP). Glaucoma, a leading cause of blindness worldwide, is associated with changes in the ECM of the TM. The elastic modulus indicates glaucomato...
ORGANISM(S): Homo sapiens (Human) 
2018-01-22 | PXD006424 | Pride
Transcriptome study of iPSC-CMs under biochemical and biomechanical maturation conditions
Keratoconus (KC) is a chronic and degenerative condition marked by pathological weakening, thinning, and protrusion of the corneal tissue. Corneal biomechanical weakness constitutes a hallmark of early keratoconus (KC) stages, which has underlined the importance of the study of biomechanical respons...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD049296 | Pride
This analysis compared cardiomyocytes derived from induced pluripotent stem cells under biochemical and biomechanical conditions expected to induced maturation.
ORGANISM(S): Homo sapiens 
2021-09-15 | GSE183398 | GEO
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