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TranscriptomicsComparative transcriptome and network biology analyses demonstrate antiproliferative and hyperapoptotic phenotypes in human keratoconus corneas
Comparative transcriptome between Keratoconus and control corneas
ORGANISM(S): Homo sapiens 
2011-08-17 | E-MEXP-2777 | biostudies-arrayexpress
ProteomicsTear protein profile in eyes with keratoconus after one year of intrastromal corneal ring and corneal crosslinking: a pilot study
Keratoconus (KC) is a corneal ectasia characterized by structural changes, resulting in progressive thinning and biomechanical weakening that can lead to worsening visual acuity due to irregular astigmatism. Corneal collagen Crosslinking (CXL) and Intracorneal Ring Segment (ICRS) are widely used tr...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035655 | Pride
Keratoconus Intracorneal ring segment Crosslinking Tear film 
ProteomicsProteomic Analysis of Tear Fluid from the Offspring of Keratoconus Patients Toward Novel Biomarkers and Pathways Associated with Corneal Biomechanical Weakness and Disease Susceptibility.
Keratoconus (KC) is a chronic and degenerative condition marked by pathological weakening, thinning, and protrusion of the corneal tissue. Corneal biomechanical weakness constitutes a hallmark of early keratoconus (KC) stages, which has underlined the importance of the study of biomechanical respons...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD049296 | Pride
Offspring Keratoconus Biomarkers Proteomics Tear fluid 
GenomicsPhenotypic and Genotypic Analysis of Keratoconus
Phenotypic and Genotypic Analysis of Keratoconus
PRJNA916336 | ENA
GenomicsPhenotypic and Genotypic Analysis of Keratoconus
Phenotypic and Genotypic Analysis of Keratoconus
PRJNA916337 | ENA
GenomicsStudy on m6A methylation modification of keratoconus
Study on m6A methylation modification of keratoconus
PRJNA752732 | ENA
MetabolomicsQuantitative metabolomic analysis of the human cornea and aqueous humor
INTRODUCTION: Cornea is the outermost part of the eye supplied mostly by aqueous humor (AH). Therefore, the comparison of the metabolomic compositions of AH and cornea may help to determine which compounds are produced inside the cornea, and which penetrate into cornea from AH for intra-corneal cons...
2018-06-20 | MTBLS444 | MetaboLights
GenomicsEye-conic' spatial transcriptomics of keratoconus corneas
Eye-conic' spatial transcriptomics of keratoconus corneas
PRJNA1293390 | ENA
TranscriptomicsmiRNA Profile in Three Different Normal Human Ocular Tissues by miRNA-Seq
Since microRNAs (miRNAs) have been associated with eye diseases, our study aims to profile ocular miRNA expression in normal human eye tissue using miRNA-Seq in order to provide a foundation for future disease research. Total RNAs were extracted from normal human ciliary body (CB) (n=7), cornea (n=7...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-81254 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients
We compared the transcriptome of keratoconus and control epithelium using RNA-Seq. Epithelial tissues were obtained prior to surgery from keratoconus and myopia control patients, undergoing collagen cross-linking and photorefractive keratectomy, respectively. We identified major differences in kerat...
ORGANISM(S): Homo sapiens 
2018-05-10 | GSE112155 | GEO
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