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MetabolomicsFunctional Metabolomics Describes the Yeast Biosynthetic Regulome
Genome-metabolism interactions enable cell growth. To probe the extent of these interactions and delineate their functional contributions, we quantified the Saccharomyces amino acid metabolome and its response to systematic gene deletion. Over one-third of coding genes, in particular those important...
2017-03-02 | MTBLS434 | MetaboLights
MetabolomicsDynamic metabolic and transcriptomic profiling reveals the biosynthetic characteristics of hydroxycinnamic acid amides (HCAAs) in sunflower pollen

Sunflower pollen is a natural nutritious food with a long history and multiple functions, however, the main chemical components apart from flavonoids and their biosynthesis processes have not been thoroughly investigated. In this study, seven hydroxycinnamic acid amides (HCAAs) (1-7) abundant in ...

2021-10-15 | MTBLS3075 | MetaboLights
TranscriptomicsGlobal analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways
The eubacterial species Streptomyces coelicolor proceeds through a complex growth cycle in which morphological differentiation/development is associated with a transition from primary to secondary metabolism and the production of antibiotics. We used DNA microarrays and mutational analysis to invest...
ORGANISM(S): Streptomyces coelicolor 
2005-07-23 | E-GEOD-2983 | biostudies-arrayexpress
ProteomicsMetabolic characterization of two white-rot fungi in diverse cultivation environments reveals biotechnologically relevant biosynthetic pathways
Two white-rot fungi, Trametes versicolor and Gelatoporia subvermispora, were cultivated in different environments - agitation and static incubation modes and variations in the level of antioxidants - during the conversion of a lignin-related aromatic compound and cellobiose. Both incubation mode and...
ORGANISM(S): Gelatoporia Subvermispora (ncbitaxon:42742) Trametes Versicolor (ncbitaxon:5325) 
2024-08-05 | MSV000095519 | MassIVE
UnknownTemporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle.
Not available
S-EPMC9970877 | biostudies-literature
TranscriptomicsIntegrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and subsequent gamete fertilisation in mosquitoes is essential for the spreading of the disease. The molecular processes orchestrating these transitions are far from fully understood. Here we report the first transcr...
ORGANISM(S): Plasmodium falciparum 
2016-06-28 | E-GEOD-75795 | biostudies-arrayexpress
ProteomicsIdentification of carcinogenesis and tumor progression processes in pancreatic ductal adenocarcinoma using high-throughput proteomics
Pancreatic adenocarcinoma (PDAC) is an aggressive disease with an overall 5 year-survival rate of just 5%. A better understanding of both the carcinogenesis processes and the mechanisms of progression of PDAC disease is mandatory. For this, proteomics data from FFPE samples of 173 primary tumor, nor...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-15 | MSV000096431 | MassIVE
Unknown20-Hydroxyecdysone Boosts Energy Production and Biosynthetic Processes in Non-Transformed Mouse Cells.
Not available
S-EPMC11591052 | biostudies-literature
UnknownLate-life dietary folate restriction reduces biosynthetic processes without compromising healthspan in mice.
Not available
S-EPMC10802571 | biostudies-literature
UnknownThe effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.
Not available
S-EPMC5878011 | biostudies-literature
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