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ProteomicsComparative proteomics of common allergenic tree pollens of birch, alder and hazelComparative proteomics of common allergenic tree pollens of birch, alder and hazel
It is known that, in addition to known allergens, other proteins in pollen can aid the development of an immune response in allergenic individuals. The contribution of the “unknown” protein allergens becomes especially prominent in phylogenetically related species where, despite of high homology of ...
ORGANISM(S): Alnus glutinosa Corylus avellana Betula pendula 
2021-04-21 | PXD021133 | Pride
Birch Alder Proteomics Pollen Hazel 
TranscriptomicsAntigen specific human conventional T cells (CD154+) or regulatory T cells (CD137+) directed agains A. fumigatus or Birch pollen lysate isolated from Birch pollen allergic patients or healthy controls.
Foxp3+ regulatory T cells (Treg) play a central role for tolerance against self and innocuous environmental antigens. However, the role of antigen-specificity for Treg-mediated tolerance is only incompletely understood. Here we show by direct ex vivo characterization of human CD4+ T cells, that the ...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-GEOD-77018 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of nose epithelial cells from people who are birch pollen allergic or non-allergic after exposure to natural pollen in spring and winter
Immunologic response of two patient categories, birch pollen allergic and non-allergic, to natural pollen exposure (spring vs. winter) quantitated at the level of the transcriptome
ORGANISM(S): Homo sapiens 
2009-04-14 | E-MTAB-17 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of nasal mucosa in birch pollen allergic and non-allergic individuals upon nasal provocation with birch pollen
Birch pollen is a significant cause of allergic rhinitis, yet the mechanisms of sensitization is to be understood completely. Here, we investigate the changes in gene expression of birch pollen allergic and non-allergic individuals that occur as a result of nasal provocation with birch pollen.
ORGANISM(S): Homo sapiens 
2024-12-17 | GSE261239 | GEO
GenomicsGene expression analysis of nasal mucosa in birch pollen allergic and non-allergic individuals upon nasal provocation with birch pollen
Gene expression analysis of nasal mucosa in birch pollen allergic and non-allergic individuals upon nasal provocation with birch pollen
PRJNA1086145 | ENA
TranscriptomicsExposure of Air-Liquid-Interface bronchial epithelial cells to whole birch pollen
Human BEAS-2B were exposed to whole birch pollen using a Pollen Sedimentation Chamber. The chamber was designed to be able to dose cells to dry whole pollen. The goal was to understand the reaction of human epithelial cells to a human real life pollen exposure.
ORGANISM(S): Homo sapiens 
2021-11-03 | GSE179942 | GEO
GenomicsExposure of Air-Liquid-Interface bronchial epithelial cells to whole birch pollen
Exposure of Air-Liquid-Interface bronchial epithelial cells to whole birch pollen
PRJNA745951 | ENA
ProteomicsmoDCs HPLC-MS/MS - Unbiased Quantitative Proteomics Reveals a Crucial Role of the Allergen Context for the Activation of Human Dendritic Cells
To investigate the allergenicity of the major birch pollen allergen Bet v 1 and the impact of known adjuvants coming from pollen, such as lipopolysaccharide (LPS), we performed quantitative proteome analysis of stimulated monocyte-derived dendritic cells (moDCs). Thus, we treated cells with birch po...
ORGANISM(S): Homo sapiens (Human) 
2017-12-01 | PXD006196 | Pride
Human Modc Hplc-ms/ms 
Genomics
Birch pollen microbiome
PRJEB38783 | ENA
UnknownQuantitative DNA Analyses for Airborne Birch Pollen.
Not available
S-EPMC4619600 | biostudies-literature
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