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MetabolomicsIdentification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine

INTRODUCTION: Bitter melon (Momordica charantia, Cucurbitaceae) is a popular edible medicinal plant, which has been used as a botanical dietary supplement for the treatment of diabetes and obesity in Chinese folk medicine. Previously, our team has proved that cucurbitanes triterp...

2019-10-24 | MTBLS701 | MetaboLights
MetabolomicsMechanism of Organic Plant Protection Technology in Controlling Apple Bitter Pit: Insights from Integrated Transcriptomic and Metabolomic Analyses

Apple bitter pit (ABP), a severe physiological disorder, severely impairs the quality and yield of the susceptible 'Qingcui' apple. This study investigated the control efficacy and mechanism of a three-in-one Organic Plant Protection Technology (OPPT) against ABP, with treatments set as control (...

2026-02-26 | MTBLS13937 | MetaboLights
MetabolomicsA new method for quantitative determination of bitter components of Belgian endive, with a focus on sesquiterpene oxalates
The sesquiterpene lactones typical of the genera Cichorium and Lactuca were historically thought to be present in the free and glycosylated form, but recent developments have highlighted the presence of highly unusual oxalyl esters. In this work, first a liquid chromatography method that requires mi...
2016-01-04 | MTBLS270 | MetaboLights
MetabolomicsA high-fat diet induced obesity murine model treated with bitter melon (Momordica charantia)
Not available
ORGANISM(S): Mus musculus 
ST001911 | MetabolomicsWorkbench
ProteomicsMini-Scale Cheese Peptidomics Reveals Strain-Specific Bitter Peptide Profiles During Cheese Aging
This study investigated the impact of individual lactococcal starter cultures on peptide formation and bitter peptide accumulation during cheese aging using a novel mini-scale cheese production system. Cheeses were produced using single-strain fermentations of Lactococcus lactis and Lactococcus crem...
ORGANISM(S): Bos taurus (Bovine) 
2026-08-01 | PXD079655 | Pride
Lactococcus lactis Peptidomics Casein proteolysis Proteomexchange Lactococcus cremoris Cheese Bitter peptides Dairy proteomics Cheese aging Lc-ms/ms 
TranscriptomicsRNA-Seq on Malus domestica Braeburn x Cameo lines resistant and susceptible to bitter pit disorder
Bitter pit is the most important physiological disorder affecting apples. In order to ascertain the genetic bases of its incidence in apple fruit, a mapping population of ‘Braeburn’ (susceptible to bitter pit) × ‘Cameo’ (resistant to bitter pit) cultivars was used to map the trait over two growing s...
ORGANISM(S): Malus domestica 
2018-06-12 | E-MTAB-6190 | biostudies-arrayexpress
TranscriptomicsRNAseq of Drosophila Sweet and Bitter Gustatory Second Order Neurons
The dataset contains RNAseq data derived from Drosophila melanogaster Gustatory Second Order Neurons (G2Ns). G2Ns were labelled using the trans-TANGO technique using the Gr64f-Gal4 and Gr66a-Gal4 transgenes for sweet and bitter gustatory neurons respectively. G2Ns labelled with trans-TANGO (tomato) ...
ORGANISM(S): Drosophila melanogaster 
2025-06-28 | E-MTAB-15220 | biostudies-arrayexpress
GenomicsRAD 423 samples of Bitter gourd
RAD F2 423 sample of Bitter gourd (Momordica charantia)
PRJEB23602 | ENA
GenomicsInflammation induces bitter taste oversensitization via epigenetic changes in Tas2r gene clusters
T2R bitter receptors, encoded by Tas2r genes, are not only critical for bitter taste signal transduction but also important for defense against bacteria and parasites. However, little is known about whether and how Tas2r gene expression are regulated. Here, using single-cell assays for transposase-a...
ORGANISM(S): Mus musculus 
2023-05-25 | GSE213404 | GEO
GenomicBitter Blockers (BB)

The goal of this project is to determine variation in human bitter perception and the effectiveness of bitter blockers in individuals of different genotypes. The project is based on the parent project titled "Efficacy of bitter taste blockers on flavor acceptance in pediatric population", which a...

phs000839 | dbGaP
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