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We performed comprehensive genome-scale DNA methylation profiling by Illumina Infinium HumanMethylation27 of 18 DNA pools that represent 84 colorectal cancer (CRC) samples divided according to their high-, intermediate-, and low-methylation epigenotypes (HME, IME, and LME, respectively) and 3 pools ...
ORGANISM(S): Homo sapiens 
Congenital heart disease (CHD) is the most frequent birth defect and affects nearly 1% of newborns. The etiology of CHD is largely unknown and only a small percentage can be assigned to environmental risk factors such as maternal diseases or exposure to mutagenic agents during pregnancy. Chromosomal...
ORGANISM(S): Homo sapiens 
AML/MDS patients carrying 11q amplifications involving the mixed lineage leukemia gene (MLL) locus are characterized by a complex aberrant karyotype (CAK) frequently including deletions within 5q, 17p and 7q, a later onset and fast progression of the disease with extremely poor prognosis. We and oth...
ORGANISM(S): Homo sapiens 
Regional identity of human neural stem cells determinesoncogenic responses to histone 1H3.3 mutants
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021270 | Pride
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