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TranscriptomicsMessenger RNA profiling of bovine endometrium during the estrous cycle using a custom-made cDNA array
The endometrium provides optimal conditions for the transport of sperm to the oviduct, to the site of fertilization, and later on for the reception of the embryo. To study these changes on the level of gene expression, a messenger RNA expression profiling of endometrium tissue samples collected from...
ORGANISM(S): Bos taurus 
2010-05-27 | E-GEOD-8337 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of skeletal myoblast differentiation and exposure to TNF-alpha or IGF1
Skeletal myocyte differentiation involves fusion of myoblasts to multinucleated myotubes. In vitro differentiation can be induced by serum withdrawal. The differentiation process is negatively regulated by pathological concentrations of TNF-alpha but can be positively regulated by IGF1. This study f...
ORGANISM(S): Mus musculus 
2015-04-05 | E-MTAB-3474 | biostudies-arrayexpress
TranscriptomicsExpression data from primary bovine mammary epithelial cells (pbMEC) challenged with heat inactivated E. coli and S. aureus particles
Infections of the udder by Escherichia coli very often elicit acute inflammation, while Staphylococcus aureus infections tend to cause mild, subclinical inflammation and persistent infections. The molecular causes undercovering the different disease patterns are poorly understood. We therefore profi...
ORGANISM(S): Bos taurus 
2012-09-07 | E-GEOD-25413 | biostudies-arrayexpress
TranscriptomicsFine mapping of genome activation in bovine embryos by RNA sequencing
During maternal-to-embryonic transition control of embryonic development gradually switches from maternal RNAs and proteins stored in the oocyte to gene products generated after embryonic genome activation (EGA). Detailed insight into the onset of embryonic transcription is obscured by the presence ...
ORGANISM(S): Bos taurus 
2014-02-09 | E-GEOD-52415 | biostudies-arrayexpress
TranscriptomicsCapture-C identification of chromatin interactions of 53 selected cellular loci prior to and post induction of EBV's lytic cycle in Raji cells
Identification of specific chromatin interactions of 53 selected genes with the Capture-C technique in Raji iBZLF1 cells prior to and 6 or 15 h after induction of EBV’s lytic cycle. The experiments were performed as triplicates.
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7825 | biostudies-arrayexpress
TranscriptomicsRNA-seq in Raji cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline
(i) RNA transcripts of Raji iBZLF1 cells (https://www.biorxiv.org/content/10.1101/573659v1) were compared between non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Human (Hg19) as well as viral (EBV, Raji KF717093.1) transcripts were analyzed. Artificial ERCC Spike-ins (Ther...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-7820 | biostudies-arrayexpress
TranscriptomicsBovine endometrium at day 18 of pregnancy after transfer of in vitro produced or somatic cell nuclear transfer embryos
Although somatic cell nuclear transfer (SCNT) cloning is more efficient in bovine than in all other species tested so far, there is a high rate of pregnancy failure that has been linked to structural and functional abnormalities of the placenta. We tested the hypothesis that these changes may origin...
ORGANISM(S): Bos taurus 
2009-03-12 | E-GEOD-13663 | biostudies-arrayexpress
TranscriptomicsATAC-seq analyses with results from DG75 cells prior to and post induction of two versions of BZLF1.
The aim of the experiment was to identify accessible (open) chromatin regions in the genome prior to and post induction of EBV's BZLF1 protein. Two versions of BZLF1 were employed: full-length and activation-domain (AD)-truncated BZLF1 non-induced and induced for 15 h. The experiments were performed...
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8420 | biostudies-arrayexpress
TranscriptomicsStem cell factor Sox2 regulates the tumorigenic potential in human gastric cancer cells
Gastric cancer is still one of the most common causes of cancer-related death worldwide, which is mainly attributable to late diagnosis and poor treatment options. Infection with H. pylori, different environmental factors and genetic alterations are known to influence the risk of developing gastric ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-42937 | biostudies-arrayexpress
TranscriptomicsBeta-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/beta-catenin signaling
To validate the suitability of two commonly used colorectal cancer cell lines, DLD1 and SW480, as model systems to study colorectal carcinogenesis, we treated these cell lines with beta-catenin siRNA and identified beta-catenin target genes using DNA microarrays. The list of identified target genes ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-44097 | biostudies-arrayexpress
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