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TranscriptomicsTranscription profiling of human myeloma cell line IH-1 response to BMP-4
The IL-6-dependent human myeloma cell line IH-1 was stimulated with BMP-4 (50 ng/ml) for four hours and compared to control cells.
ORGANISM(S): Homo sapiens 
2004-09-01 | E-MEXP-124 | biostudies-arrayexpress
ProteomicsBMP1/Tolloid-like substrates by iTRAQ degradomics
In this study, we used an iTRAQ-based quantitative proteomic approach to reveal the release of proteolytic fragments from the cell surface or the ECM by BMP-1. Thirty-seven extracellular proteins were found in significantly higher or lower amounts in the conditioned medium of HT1080 cells overexpres...
ORGANISM(S): Homo sapiens (Human) 
2014-09-29 | PXD000786 | Pride
Tfg-beta Protease Bmp-1 Itraq Itraq-atoms 
TranscriptomicsFull genome time series analysis of the mulitple myeloma cell line IH-1 stimulated with BMP-4/IL6 or BMP-4/IL15
We sought to find the mechanism for BMP-induced apoptosis in multiple myeloma by doing a gene expression time-course study. Experiment overall design: The myeloma cell line IH-1 was treated with BMP-4/IL-6 or BMP-4/IL-15 for 0, 0.5, 1, 2, 4 and 8 hrs (at 8 h also untreated cells).
ORGANISM(S): Homo sapiens 
2011-12-01 | E-MTAB-619 | biostudies-arrayexpress
GenomicsCXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development
CXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development
PRJNA1305733 | ENA
TranscriptomicsRNA-seq of small intestinal organoids treated with IL-13 for 0, 1, 4 8 and 24 hours and with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we investigate ...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-10455 | biostudies-arrayexpress
UnknownSMOC-1 interacts with both BMP and glypican to regulate BMP signaling in C. elegans.
Not available
S-EPMC10464977 | biostudies-literature
UnknownC. elegans SMOC-1 interacts with both BMP and glypican to regulate BMP signaling.
Not available
S-EPMC9881921 | biostudies-literature
UnknownWISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity.
Not available
S-EPMC3179320 | biostudies-literature
TranscriptomicsCXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development
The mechanisms mediating endochondral bone formation remain incompletely understood. Here, we show that CXXC Finger Protein 1 (CFP1) is required for the onset of chondrogenesis during forelimb development. CFP1-deficient mesenchymal progenitor cells (LMPs) retain an immature molecular signature with...
ORGANISM(S): Mus musculus 
2026-08-13 | GSE305429 | GEO
UnknownBmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.
Not available
S-EPMC5560993 | biostudies-literature
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