Sort   by:  
 Page size 
ProteomicsMultifactorial neuroprotective effects of BNN27, a Nerve Growth Factor mimetic, in the 5xFAD mouse model of Alzheimer’s Disease
Neurotrophic factors consist major regulatory molecules and their decline in Alzheimer's disease is considered as an important cause of disease progression. Novel pharmacological approaches are targeting the downstream pathways controlled by neurotrophins, such as nerve growth factor (NGF) receptors...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-25 | PXD044699 | Pride
Mouse Proteomics Brain Hippocampus Lc-ms Bnn27 5xfad Directdia 
UnknownAnalgesic and Anti-Inflammatory Effects of the Synthetic Neurosteroid Analogue BNN27 during CFA-Induced Hyperalgesia.
Not available
S-EPMC8469064 | biostudies-literature
UnknownBNN27, a 17-Spiroepoxy Steroid Derivative, Interacts With and Activates p75 Neurotrophin Receptor, Rescuing Cerebellar Granule Neurons from Apoptosis.
Not available
S-EPMC5183592 | biostudies-literature
UnknownMicroneurotrophin BNN27 Reduces Astrogliosis and Increases Density of Neurons and Implanted Neural Stem Cell-Derived Cells after Spinal Cord Injury.
Not available
S-EPMC10135698 | biostudies-literature
UnknownDevelopment and Comparative In Vitro and In Vivo Study of BNN27 Mucoadhesive Liposomes and Nanoemulsions for Nose-to-Brain Delivery.
Not available
S-EPMC9967044 | biostudies-literature
UnknownMultimodal beneficial effects of BNN27, a nerve growth factor synthetic mimetic, in the 5xFAD mouse model of Alzheimer's disease.
Not available
S-EPMC12092300 | biostudies-literature
UnknownMicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.
Not available
S-EPMC5055348 | biostudies-literature
UnknownA quest for the stereo-electronic requirements for selective agonism for the neurotrophin receptors TrkA and TrkB in 17-spirocyclic-dehydroepiandrosterone derivatives.
Not available
S-EPMC10568017 | biostudies-literature
TranscriptomicsModelling glucose neurotoxicity in iPSC-derived dopaminergic neurons and glia cells reveals the neuroprotective potential of p75NTR targeting
Hyperglycemia, a hallmark of Diabetes Mellitus, consists a metabolic condition that can lead to severe complications in the nervous system, significantly increasing the risk for neurodegenerative disorders. Evidence from epidemiological studies and animal models suggests that diabetes influences the...
ORGANISM(S): Homo sapiens 
2026-03-31 | GSE291145 | GEO
GenomicsModelling glucose neurotoxicity in iPSC-derived dopaminergic neurons and glia cells reveals the neuroprotective potential of p75NTR targeting
Modelling glucose neurotoxicity in iPSC-derived dopaminergic neurons and glia cells reveals the neuroprotective potential of p75NTR targeting
PRJNA1232088 | ENA
Sort   by:  
 Page size