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Bone Marrow Interstital Fluid from 120 patients with various plasma cell dyscrasias were assessed using Seer's Proteograph XT platform and an LC-MS system. For each sample, two MS injections were performed, one for each nanoparticle incubation used in the Proteograph XT.
ORGANISM(S): Homo sapiens (Human) 
2025-10-21 | PXD059339 | Pride
Multiple myeloma (MM) is a plasma cell associated cancer and the second most common hematological malignancies. Although researchers have been working on MM, comprehensive quantitative proteomic analysis of Bone Marrow Interstitial Fluid (BMIF) and Blood Serum is not yet reported. Being a proximal b...
ORGANISM(S): Homo sapiens (Human) 
2021-01-26 | PXD008927 | Pride
Neonatal bone marrow interstitial fluid supports expansion and osteogenic ability of human bone marrow mesenchymal stromal cells
The bone marrow microenvironment is critical for the maintenance and functionality of stem/progenitor cells, which is essential for bone development and regeneration. However, the composition and potential use of bone marrow interstitial fluid have not been extensively explored. In this study, we re...
ORGANISM(S): Homo sapiens 
2025-12-30 | GSE290284 | GEO
Granulocyte-Macrophage colony stimulating factor (GM-CSF) devlops heterogenous myeloid cell populations from bone marrow progenitor cells. In vitro generated bone marrow derived cells are excellent sources for obtaining dendritic cells or macrophages, but it is still not clear about the exact mixed ...
ORGANISM(S): Mus musculus 
The mechanisms by which dendritic cells (DCs) induce differentiation of naïve CD4+ T cells along the Th2 lineage is not well understood given that DCs themselves do not produce IL-4. In the present study, we undertook a microarray approach to identify genes involved in the induction of Th2 differe...
ORGANISM(S): Mus musculus 
Dendritic cells isolated from murine bone marrow were cultured for 7 days and then stimulated with 100 ng/mL LPS for 24h. Cells were derived from either wildtype or microRNA-146a knock-out mice. Total RNA was isolated from the cells following stimulation.
ORGANISM(S): Mus musculus 
In dogs, a species for which markers of cell populations are often limiting, we sought to evaluate in an unbiased way the heterogeneity of cell subpopulations in the bronchoalveolar lavage fluid of healthy dogs, by single-cell RNA-sequencing.
ORGANISM(S): Canis lupus familiaris 
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