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MetabolomicsA bovine plasma-derived serum substitute enables continuous manufacturing of cultivated fish biomass
Cultivated fish meat offers a sustainable solution to marine stock depletion, yet industrial scalability is limited by the prohibitive cost of fetal bovine serum (FBS). We developed a cost-effective bovine plasma-derived serum substitute (bPCPE-LTUS) through low-temperature ultrasonication. This phy...
2026-09-25 | MTBLS14288 | MetaboLights
ProteomicsIn-depth proteome analysis of Hela cell culture conditioned media containing fetal bovine serum.
We performed DIA-MS based proteomic analysis of Hela cells conditioned media containing fetal bovine serum by albumin (Alb)-depletion and non-depletion. In addition, we attempted to enrich secreted proteins by reducing the volume of culture medium (10mL, 5mL and 2mL). The supernatants of each cultur...
ORGANISM(S): Homo Sapiens (human) 
2022-02-22 | PXD024272 | JPOST Repository
TranscriptomicsAdult bovine serum (10%) alters the expression of Pseudomonas aeruginosa genes
As production of virulence factors by Pseudomonas aeruginosa is influenced by the host environment, we examined the effect of 10% adult bovine serum (ABS) on the global transcription with P. aeruginoas PAO1 at different phases of growth. At early exponential phase (4 h), serum significantly enhance...
ORGANISM(S): Pseudomonas aeruginosa 
2012-07-08 | E-GEOD-30698 | biostudies-arrayexpress
ProteomicsDefining albumin as a glycoprotein with multiple N-linked glycosylation sites
Background Plasma proteins can be modified by addition of sugar residues by non-enzymatic glycation as well as glycosylation. While glycation is a hallmark of hyperglycemia, glycosylation is a complex, enzyme-catalyzed post-translational modification by heterogeneous sugar chains and is present on ...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Oryctolagus cuniculus (Rabbit) 
2024-06-16 | PXD047863 | Pride
Microheterogeneity Glycoproteomics Novel glycosylation site Hsa Human serum albumin Bsa 
TranscriptomicsAlbumin, TGF-Beta1 and Blood-Brain Barrier opening induce cortical epileptogenesis.
Insults to the cerebral cortex, such as trauma, ischemia or infections, may result in the development of epilepsy, one of the most common neurological disorders. Previous studies have suggested that perturbations in neurovascular integrity and breakdown of the blood-brain barrier (BBB) lead to neuro...
ORGANISM(S): Rattus norvegicus 
2009-07-15 | E-GEOD-12304 | biostudies-arrayexpress
ProteomicsSuperoxide-induced covalent modifications of bovine serum albumin by QMP-SO
We have developed QMP-SOs, a new class of superoxide-specific probes capable of proximity labelling and chemoproteomic profiling of proteins associated with superoxide redox biology. In this experiment, we performed shotgun proteomics experiment to investigate covalent modifications of amino acid on...
ORGANISM(S): Bos taurus (Bovine) 
2024-08-01 | PXD052283 | Pride
Covalent modifications of amino acid residues on bovine serum albumin by a superoxide-specific probe Qmp-so 
TranscriptomicsTranscription profiling of mouse jejunum detached peyers patch from mice orally administered lactoperoxidase (LPO) to study influence of bovine LPO on the digestive tract.
Lactoperoxidase (LPO) is a component of milk and other external secretions. Recently, we found antiinflammatory effect of orally administered LPO in mouse model of influenza virus-induced pneumonia. In order to study influence of bovine LPO on the digestive tract as its possible target organ, we per...
ORGANISM(S): Mus musculus 
2007-11-13 | E-GEOD-5562 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human endothelial cell monolayers treated with homocysteinylated albumin
Endothelial cells monolayers were incubated, for 18h, in the presence of 1.0 ?M N-homocysteinylated albumin. Negative controls were cells incubated with unmodified human serum albumin at a comparable protein concentration and untreated cells.
ORGANISM(S): Homo sapiens 
2011-06-07 | E-MEXP-2771 | biostudies-arrayexpress
ProteomicsOilseed protein isolates as albumin alternatives for muscle cell culture media
The development of cost-effective serum-free media is essential for the development of cell-cultured meat technologies. While some effective media have been developed for relevant cells (e.g., bovine muscle stem cells), these rely on costly recombinant albumin which is too expensive for a scalable s...
ORGANISM(S): Glycine max Gossypium hirsutum Brassica napus (Rape) 
2023-03-25 | PXD036518 | Pride
Rapeseed protein isolate Serum-free cell culture Culture media Soybean protein isolate Albumin Cultured meat Cottonseed protein isolate 
MetabolomicsSequential lipidomic, metabolomic, and proteomic analyses of serum, liver, and heart tissue specimens from peroxisomal biogenesis factor 11α knockout mice
Peroxisomes are versatile single membrane-enclosed cytoplasmic organelles, involved in reactive oxygen species (ROS) and lipid metabolism and diverse other metabolic processes. Peroxisomal disorders result from mutations in Pex genes-encoded proteins named peroxins (PEX proteins) and single peroxiso...
2022-02-02 | MTBLS1887 | MetaboLights
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