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Object. Detailed and exact mechanisms underlying brain arteriovenous malformations (bAVM) are still confusing in clinic. Understanding the quantitative changes of proteins and signaling pathways would provide useful information for clinicians to understand the formation and development of bAVM and t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080716 | MassIVE
Brain Arteriovenous Malformation Genetics Study
Brain Arteriovenous Malformation Genetics Study
Gene expression profiling of endothelial-mesenchymal transition in cerebral arteriovenous malformation
This study presents a quantitative proteomic analysis of human brain arteriovenous malformation (AVM) tissues with different rupture status. Surgically resected AVM specimens from ruptured and unruptured lesions were subjected to protein extraction, enzymatic digestion, and liquid chromatography–tan...
ORGANISM(S): Homo sapiens (Human) 
2026-02-15 | PXD074343 | Pride
To investigate the endothelial-mesenchymal transition in cerebral arteriovenous malformation. We performed gene expression profiling analysis using the data obtained from RNA-seq of CD31+CD45- brain cells in Cdh5cre;Mgpflox/flox mice with or without tamoxifen induction.
ORGANISM(S): Mus musculus 
2024-05-30 | GSE262300 | GEO
Brain arteriovenous malformation (BAVM) is a high-flow vascular shunt that predisposes to intracranial hemorrhage and represents a leading cause of stroke in young adults. Somatic mutations in KRAS or BRAF drive endothelial dysfunction and lesion formation, yet the contribution of non-endothelial ce...
ORGANISM(S): Mus musculus 
2026-04-27 | GSE326421 | GEO
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