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MetabolomicsMultiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level (Metabolite profiling)

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9830 | MetaboLights
MetabolomicsTen Mouse Organs Proteome and Metabolome Atlas from Adult to Aging

The complexity of the aging process, encompassing numerous organs and systems, poses a significant challenge in identifying and targeting key factors that drive age-related decline. The multi-organ synchronous molecular intricacies underlying natural aging remain elusive. Here we presented a data...

2025-08-29 | MTBLS10642 | MetaboLights
MetabolomicsMultiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level (Amino acid profiling)

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically very heterogenous. The application of omics technologies - mainly studying nucleic acids - has significantly improved MB classification and stratification, but treatment options are still unsatisfactor...

2024-05-30 | MTBLS9836 | MetaboLights
MetabolomicsNeuroactive metabolites and bile acids are altered in extremely premature infants with brain injury

The gut microbiome has been associated with pathological neurophysiological evolvement in extremely premature infants suffering from brain injury. The exact underlying mechanism and its associated metabolic signatures in infants are not fully understood. To decipher metab...

2023-12-30 | MTBLS7560 | MetaboLights
ProteomicsCell-type and brain-region resolved mouse brain proteome
To understand the complexity of the brain, connectome and transcriptome maps of high resolution are being generated, but an equivalent catalogue of the brain proteome is lacking. To provide a starting point, we have performed an in-depth proteome analysis of the adult mouse brain, its major regions ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084941 | MassIVE
ModelsUhlén2015 - Human tissue-based proteome metabolic network - brain
Uhlén2015 - Human tissue-based proteome metabolic network - brain Human brain specific proteome metabolic network This model is described in the article: Tissue-based map of the human proteome Uhlén M, Fagerberg L, Hallström BM, Lindskog C, Oksvold P, Mardinoglu A, Siver...
2015-01-28 | MODEL1411240032 | BioModels
ProteomicsProteome analysis of adult mouse brain capillaries
Isolated brain capillaries are essential for analyzing the changes of protein expressions at the blood-brain barrier (BBB) under pathological conditions. The standard brain capillary isolation methods require the use of at least 5 mouse brains in order to obtain a sufficient amount and purity of bra...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-12 | PXD041770 | JPOST Repository
ProteomicsCell-type and brain-region resolved mouse brain proteome
To understand the complexity of the brain, connectome and transcriptome maps of high resolution are being generated, but an equivalent catalogue of the brain proteome is lacking. To provide a starting point, we have performed an in-depth proteome analysis of the adult mouse brain, its major regions ...
ORGANISM(S): Mus musculus (Mouse) 
2015-10-29 | PXD001250 | Pride
Brain regions Mouse Brain Neuron Q exactive Cns Oligodendrocyte Microglia Astrocyte 
ProteomicsProteome analysis of neonatal mouse brain and brain capillaries
The functions and protein expressions of the blood-brain barrier are changed during brain development after birth. The purpose of the present study was to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries by quan...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-12 | PXD039296 | JPOST Repository
ProteomicsProteome changes during mouse brain aging
Analysis of proteome changes during mouse brain aging
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000082968 | MassIVE
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