Sort   by:  
 Page size 
In this project we provide profiling of brain-derived and circulating EVs LC-MS/MS data from mice subjected to bilateral common carotid stenosis (BCAS) and Sham controls. Furthermore, data from brain-derived EVs of early AD and mixed dementias (AD+CVD) is also provided.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-09-08 | PXD009093 | Pride
To further investigate the molecular mechanisms by which EVs mediated the abnormal localization of tight junction proteins and adherence junction protein, we performed miRNA microarray analysis of extracellular vesicles isolated from breast cancer cells. miRNA expression in extracellular vesicles wa...
ORGANISM(S): Homo sapiens 
In models of Parkinson’s disease (PD), angiotensin-II type-1 receptor (AT1) blockers (ARBs) mitigated the vulnerability ofdopaminergic neurons, which aligns with recent transcriptomic studies of human brains showing increased susceptibility ofdopaminergic neurons with high AGTR1 expression, and with...
ORGANISM(S): Homo sapiens (Human) 
2025-12-06 | PXD063198 | Pride
Extracellular vesicles (EVs) have gained significant attention as potential diagnostic and therapeutic tools due to their role in intercellular communication and their ability to encapsulate various biomolecules. However, the isolation of EVs from tissue remains challenging, often requiring enzymati...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-11-07 | PXD045737 | Pride
Extracellular vesicles (EVs) are a unified terminology of membrane-enclosed vesicular species ubiquitously secreted by almost every cell type and present in all body fluids. They carry a cargo of lipids, metabolites, nucleic acids and proteins for their clearance from cells as well as for cell-to-ce...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-02-17 | PXD017273 | Pride
Extracellular vesicles (EVs) are secreted by any neuronal cells in the central nervous system (CNS) for molecular clearance, cellular communications and disease spread in multiple neurodegenerative diseases, including Alzheimer’s disease (AD), although their exact molecular mechanism is poorly under...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD022349 | Pride
At this day, Alzheimer’s disease is the most prominent form of dementia worldwide. It is characterized by tau lesions that spread throughout the brain in a spatio-temporal manner. This has led to the prion-like propagation hypothesis implicating a transfer of pathological tau seeds from cell-to-cell...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD055734 | Pride
Small RNA sequencing of human and macaque brain tissue and brain-derived extracellular vesicles separated by size exclusion chromatography
Small RNA sequencing of brain-derived extracellular vesicles from post-mortem brain tissue of controls and Alzheimer's disease patients with different APOE genotypes
Sort   by:  
 Page size