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ProteomicsExtracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems
Background: Newer 3D culturing approaches are a promising way to better mimic the in vivo tumor microenvironment and to study the interactions between the heterogeneous cell populations of glioblastoma multiforme. Like many other tumors, glioblastoma uses extracellular vesicles as an intercellular c...
ORGANISM(S): Homo sapiens (Human) 
2024-04-09 | PXD047328 | Pride
Ev Extracellular vesicle Proteomics Microrna 3d organoid model Brain cancer Glioblastoma multiforme 
ProteomicsInteractions between Transport Protein Particle (TRAPP) complexes and Rab GTPases in Arabidopsis
The Transport Protein Particle II (TRAPPII) is essential for exocytosis, endocytosis, protein sorting and cytokinesis. In spite of a considerable understanding of its biological role, little is known about Arabidopsis TRAPPII complex topology and molecular function. In this study, independent proteo...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-03 | PXD013016 | Pride
Trappii Arabidopsis Co-ip Protein complex Rab gtpases Transport protein particle 
ProteomicsA cell-free platform for characterizing and producing therapeutic bacteriophages against biohazardous and antibiotic-resistant bacteria
Bacteriophages are potent therapeutics against biohazardous bacteria that are rapidly acquiring multidrug resistance. However, routine administration of bacteriophage therapy is currently impeded by a lack of safe phage production methodologies and insufficient phage characterization. We thus develo...
ORGANISM(S): Eggerthella phage P3 Enterobacteria phage T7 Escherichia coli Bacteria 
2022-07-20 | PXD019543 | Pride
E. coli Bacteriophage 
TranscriptomicsPharmacodynamic effects of GLP-1 agonist liraglutide in adolescent, prediabetic pigs
GLP-1 agonists are potent glucose-lowering agents, however, their effect on adolescent organisms needs to be clarified Transgenic pigs expressing a dominant-negative GLP receptor randomly assigned for a 90 day treatment trial with liraglutide (0.6-1.8 mg per day)/placebo
ORGANISM(S): Sus scrofa 
2015-12-31 | E-GEOD-56427 | biostudies-arrayexpress
UnknownNeutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial.
Not available
S-EPMC11797383 | biostudies-literature
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