International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden1. This pertains to clear cell renal cell carcinoma (ccRCC), fo...
Analysis of low density neutrophils and normal density neutrophils derived from the peripheral blood of GBM patients as well as matched normal density neutrophils from control patients.
FACS sorted single cell proteomes of glioblastoma derived neutrophils. Brain tissue was dissociated and individual neutrophils were FACS sorted into 384 well plates into master mix containing. The cells were later processed on the CellenOne and analysed on an Orbitrap Astral with FAIMS Pro. The data...
Mini-bulk (500 cell) analysis of low density CD10+, low density CD10-, normal density CD10+ and brain neutrophils from glioblastoma patients with matched normal density CD10+ neutrophils from controls.
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
