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MetabolomicsNicotinamide Riboside is Uniquely Bioavailable in People and Mice
Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood, liver and heart NAD+ metabolism in people and mice. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single d...
2016-09-09 | MTBLS368 | MetaboLights
GenomicsPartitioning the C. elegans genome by nucleosome modification, occupancy, and positioning
We have characterized two post-translational histone modifications in C. elegans on a genomic scale. Micrococcal nuclease digestion and immunoprecipitation were used to obtain distinct populations of single nucleosome cores, which were analyzed using massively parallel DNA sequencing to obtain pos...
ORGANISM(S): Caenorhabditis elegans 
2009-08-31 | E-GEOD-17284 | biostudies-arrayexpress
GenomicsHistone H3K9me3 ChIP-seq of young adult C. elegans wildtype, and mutants emb-4 (qm31) and hrde-1 (tm1200)
This data set was generated to study the silencing of transposable elements by the histone H3K9me3 mark and its relevance for the nuclear RNAi pathway.
ORGANISM(S): Caenorhabditis elegans 
2017-06-29 | E-MTAB-5662 | biostudies-arrayexpress
TranscriptomicsGene expression data from MCF-7 cells treated with Lacciac Acid A
Lacciac Acid A was indentified as an inhibitor of DMNT1. MCF-7 cells were treated with Lacciac Acid A (200 uM) for 5 days. Changes in gene expression were identified by using Affymetrix Human gene ST1.0 arrays. We used microarrays to determine global changes in gene expression upon treatment with La...
ORGANISM(S): Homo sapiens 
2013-09-03 | E-GEOD-45804 | biostudies-arrayexpress
TranscriptomicsNatural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways
Complex traits, including common disease-related traits, are affected by many different genes that function in multiple pathways and networks. The apoptosis, MAPK, Notch and Wnt signalling pathways play important roles in development and disease progression. At the moment we have a poor understandin...
ORGANISM(S): Caenorhabditis elegans 
2016-02-16 | E-GEOD-77905 | biostudies-arrayexpress
ProteomicsB.henselae - Whole organism, SC (Omasits,genome_res,2013)
abundance based on Spectral counting, Interaction consistency score: 8.9, Coverage: 86
ORGANISM(S): 283166 
2013-00-00 | 534428800 | PAXDB
GenomicsChIP-Seq of human embryonic stem cells of a differentiation time course with antibody against H3K4me3
H3K4me3 ChIP-Seq profiling of a directed differentiation time course converting human embryonic stem cells (hES) into immature pancreatic beta cell precursors. CyT49, a Viacyte proprietary male hESC line with normal karyotype was used.
ORGANISM(S): Homo sapiens 
2012-10-13 | E-MTAB-821 | biostudies-arrayexpress
TranscriptomicsDirected shotgun proteomics guided by RNA-Seq identifies a complete expressed prokaryotic proteome
Prokaryotes are, due to their moderate complexity, particularly amenable to the comprehensive identification of the protein repertoire expressed under different conditions. We applied a generic strategy to identify a complete expressed prokaryotic proteome, which is based on the analysis of RNA and ...
ORGANISM(S): Bartonella henselae 
2013-04-23 | E-GEOD-44564 | biostudies-arrayexpress
UnknownThe International Sexual Health And REproductive Health during COVID-19 (I-SHARE) Study: A Multicountry Analysis of Adults from 30 Countries Prior to and During the Initial Coronavirus Disease 2019 Wave.
Not available
S-EPMC9383436 | biostudies-literature
UnknownEffects of Empagliflozin on Fluid Overload, Weight, and Blood Pressure in CKD.
Not available
S-EPMC7615589 | biostudies-literature
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