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MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
UnknownPrediagnostic Plasma 25-Hydroxyvitamin D and Pancreatic Cancer Survival.
Not available
S-EPMC5012662 | biostudies-literature
TranscriptomicsComparative Validation of the D. melanogaster Encyclopedia of DNA Elements Transcript Models
The model organism Encyclopedia of DNA Elements project (modENCODE) has produced a comprehensive annotation of D. melanogaster transcript models based on an enormous amount of high-throughput experimental data. However, some transcribed elements may not be functional, and technical artifacts may lea...
ORGANISM(S): Drosophila ficusphila 
2013-02-25 | E-GEOD-44612 | biostudies-arrayexpress
TranscriptomicsAspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
Transcriptional profiling of A. nidulans comparing starvation for 0 (reference), 12 and 24 h. The main objective was to identify genes specifically regulated during starvation by atmA and xprG. The results of the experiment were further validated by real-time PCR. Experimental procedure: Three A. ni...
ORGANISM(S): Emericella nidulans 
2012-12-07 | E-GEOD-42732 | biostudies-arrayexpress
ProteomicsIntegrated Omic Analysis of a Guinea Pig Model of Heart Failure and Sudden Cardiac Death
Here we examine key regulatory pathways underlying the transition from compensated hypertrophy (HYP) to decompensated heart failure (HF) and sudden cardiac death (SCD) in a guinea pig model by integrated multi-ome analysis. Relative protein abundances from sham-operated, HYP and HF hearts were asses...
ORGANISM(S): Cavia porcellus (Guinea pig) 
2018-10-26 | PXD003980 | Pride
Heart Proteomics Cardiac Itraq 
MetabolomicsGNPS-Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses
Paper Title: Passive accumulation of alkaloids in non-toxic frogs challenges paradigms of the origins of acquired chemical defenses. Author List; Rebecca D Tarvin, Jeffrey L Coleman, David A Donoso, Mileidy Betancourth-Cundar, Karem Lopez-Hervas, Kimberly S Gleason, J Ryan Sanders, Jacqueline M Smit...
ORGANISM(S): Multiple Frog Species 
MSV000095866 | GNPS
UnknownEvaluation of a self-fitting, shape memory polymer scaffold in a rabbit calvarial defect model.
Not available
S-EPMC8742656 | biostudies-literature
ProteomicsRedox Proteome of Skeletal Muscle
Adult and aged mouse gastrocnemius muscle analysed by redox shotgun proteomics, applying a label free quantitative proteomic approach that includes a differential Cysteine labelling step allowing simultaneous identification of up and down regulated proteins between samples and also the identificatio...
ORGANISM(S): Mus musculus (Mouse) 
2014-09-04 | PXD001054 | Pride
Redox Skeletal muscle 
UnknownFrom Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology.
Not available
S-EPMC4979242 | biostudies-literature
ProteomicsLysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity
Actin was acetylated on lysine residues with acetic anhydride to determine its impaction on the contractile properties of the thin filaments including, actin's ability to undergo crossbridge cycling with myosin, actin's affinity for tropomyosin, and the impact of actin acetylation on calcium regulat...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2020-09-04 | PXD020732 | Pride
Lysine acetylation Myosin Actin Thin filament Tropomyosin In vitro motility 
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