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ProteomicsPerilous Sites: High basic Fibroblast Growth Factor level supplement Parkinson’s disease pathology and its Spread
Lewy body (LB) pathology and loss of dopaminergic neurons are imprints of Parkinson’s disease (PD). LBs are mainly comprised of alpha-Synuclein (Dijkstra et al., 2014). Strolling detection of LBs in brain regions contribute to progressive construct of PD pathology to which molecular mechanisms are n...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-07-21 | PXD015969 | Pride
Neuron Exosome Bfgf Rat 
TranscriptomicsThe direction of cross affects obesity after puberty in male but not female offspring
We investigated parent-of-origin and allele-specific expression effects on obesity and hepatic gene expression in reciprocal crosses between the Berlin Fat Mouse Inbred line (BFMI) and C57Bl/6NCrl (B6N). We sequenced mRNA extracted from liver tissue of 10 M. Musculus individuals. 4 liver samples wer...
ORGANISM(S): Mus musculus 
2015-11-11 | E-GEOD-74889 | biostudies-arrayexpress
UnknownAggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients
Not available
S-SCDT-10_1038-S44321-024-00083-5 | biostudies-other
GenomicsIntegrative analysis of small cell lung cancer
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype. We conducted integrated analysis of genome sequencing, transcriptome, and copy number analysis and found an extremely high mutation rate of 7.4±1 protein-changing mutations per million basepairs. Evidence for inactivation of TP53 and...
EGAS00001000299 | EGA
Genomicsena-DATASET-RTL-13-12-2013-10:28:27:441-48 - samples
SCLC - Whole genome sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001000703 | EGA
Genomicsena-DATASET-RTL-02-07-2015-13:42:15:919-50 - samples
SCLC - RNA sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001001431 | EGA
GenomicsSCLC_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000526 | EGA
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