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ProteomicsDeletion of miR-15a/16-1 in murine germinal center B-cells.
Given the tumor suppressing function of miR-15a/16-1 cluster, we studied its role in the germinal center B-cells that give rise to most lymphoid malignancies.
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021323 | Pride
B-cell Proteomics Mouse Germinal center 
ProteomicsEstablishment of fetomaternal tolerance via glycan-mediated B cell suppression
The immune system must be able to distinguish self from non-self. During pregnancy, the mother’s immune system does not recognize the placenta as foreign because proteins expressed by tropbholasts, the placental cells that interface with the maternal immune system, do not activate maternal T cells. ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-01-12 | PXD029966 | Pride
Lc-msms Cd22 Placenta glycoproteins Sialic acid Fetomaternal tolerance B cells 
UnknownSystematics and diversification of Anindobothrium Marques, Brooks & Lasso, 2001 (Eucestoda: Rhinebothriidea).
Not available
S-EPMC5617167 | biostudies-literature
UnknownImmune boosting by B.1.1.529 <b>(</b>Omicron) depends on previous SARS-CoV-2 exposure.
Not available
S-EPMC9210451 | biostudies-literature
UnknownmiR-15a/16-1 deletion in activated B cells promotes plasma cell and mature B-cell neoplasms.
Not available
S-EPMC8033455 | biostudies-literature
TranscriptomicsTranscriptome dynamics of developing photoreceptors in 3-D retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks
To define molecular mechanisms underlying rod and cone differentiation, we generated H9 human embryonic stem cell line carrying a GFP reporter that is controlled by the promoter of cone-rod homeobox (CRX) gene, the first known marker of post-mitotic photoreceptor precursors. CRXp-GFP reporter in H9 ...
ORGANISM(S): Homo sapiens 
2015-08-03 | E-GEOD-67645 | biostudies-arrayexpress
UnknownStereoselective synthesis of the C14-C23 fragment of biselyngbyolide A and B enabled by transition metal catalysis.
Not available
S-EPMC6327972 | biostudies-literature
UnknownTargeting Metal-Aβ Aggregates with Bifunctional Radioligand [11C]L2-b and a Fluorine-18 Analogue [18F]FL2-b.
Not available
S-EPMC4329991 | biostudies-literature
TranscriptomicsTranscription profiling of response of Rattus norvegicus frontal cortex to chronic olanzapine treatment
Male Sprague-Dawley albino rats (Charles River) initially weighting approximately 200 grams were randomly assigned to one of the following: 1) olanzapine (2 mg/kg/day, I.P.) (N=20) or 2) Saline (N=20) and administered olanzapine or saline for 21 days. Frontal cortex (N=4/group) was dissected and ho...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2547 | biostudies-arrayexpress
ProteomicsCell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone
Glioblastoma (GBM) is the most prevalent and aggressive malignant primary brain tumor. GBM proximal to the lateral ventricles (LVs) is more aggressive, potentially due to subventricular zone (SVZ) contact. Despite this, crosstalk between GBM and neural stem/progenitor cells (NSC/NPCs) is not well un...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-06-24 | PXD044773 | Pride
Metrs l274g Glioma Proteomics Lateral ventricle Stem cell niche Subventricular zone Brain cancer Neurogenesis Click chemistry Senescence 
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