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ProteomicsOnline electrochemical reduction of both inter- and intramolecular disulfide bridges in immunoglobulins
Cysteine disulfide bridges can be reduced by chemical methods, like an incubation with DTT. However, reduction with an electrochemical method has also been demonstrated. Electrochemical reduction can be implemented online, after LC separation and before mass spectrometry. For the study of antibody m...
ORGANISM(S): Homo sapiens (Human) 
2022-05-27 | PXD021649 | Pride
Electrochemical reduction  disulfide  top-down  antibody 
UnknownComparison of Mycoplasma pneumoniae Genome Sequences from Strains Isolated from Symptomatic and Asymptomatic Patients.
Not available
S-EPMC5081376 | biostudies-literature
TranscriptomicsTemporal Control of Macrophage Pro-inflammatory Phenotype by a Biphasic HIF-1α Regulatory Program
Hypoxia-inducible factor 1α (HIF-1α) broadly orchestrates metabolic reprogramming in inflammatory macrophages. However, how HIF-1α is activated in the earliest events following pattern recognition receptor activation remains unclear. We found that HIF-1α is functionally active shortly after macroph...
ORGANISM(S): Mus musculus 
2026-07-13 | E-MTAB-16172 | biostudies-arrayexpress
UnknownHemoadsorption with CytoSorb shows a decreased observed versus expected 28-day all-cause mortality in ICU patients with septic shock: a propensity-score-weighted retrospective study.
Not available
S-EPMC6749645 | biostudies-literature
UnknownWeight Change is Associated With Metabolic Liver Health in a General Population Extending Beyond Weight Loss Targets of International Guidelines.
Not available
S-EPMC12670896 | biostudies-literature
UnknownCXCL10 Secreted by Pericytes Mediates TNFα-Induced Vascular Leakage in Tumors and Enhances Extravasation of Nanoparticle-Based Chemotherapeutics.
Not available
S-EPMC12046328 | biostudies-literature
UnknownA rare missense variant in RCL1 segregates with depression in extended families.
Not available
S-EPMC5984098 | biostudies-literature
UnknownIntegrating Gut Microbiome and Metabolome to Gain Insight into Metabolic Dysfunction-Associated Steatotic Liver Disease.
Not available
S-EPMC12547235 | biostudies-literature
UnknownIntergenerational impact of childhood trauma on hair cortisol concentrations in mothers and their young infants.
Not available
S-EPMC9930158 | biostudies-literature
UnknownThe presence of CLL-associated stereotypic B cell receptors in the normal BCR repertoire from healthy individuals increases with age.
Not available
S-EPMC6714092 | biostudies-literature
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