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TranscriptomicsWhite-to-brown metabolic conversion of human adipocytes by JAK inhibition
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused considerable attention on the discovery of novel therapeutics. One promising approach has been to increase the number or activity of brown-like adipocytes in white adipose depots, as this has been...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-GEOD-57896 | biostudies-arrayexpress
ProteomicsARGLU1 RIME experiment in N2a cells
ARGLU1 is a Transcriptional Coactivator and Splicing Regulator Important for Stress Hormone Signaling and Development Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine and glutamate rich 1 (ARGLU1) in a screen for new modu...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-15 | PXD012406 | Pride
Nr3c1 Splicing Gr Arglu1 
UnknownEnvironmental Changes Recorded in Sedimentary Rocks in the Clay-Sulfate Transition Region in Gale Crater, Mars: Results From the Sample Analysis at Mars-Evolved Gas Analysis Instrument Onboard the Mars Science Laboratory Curiosity Rover.
Not available
S-EPMC11603101 | biostudies-literature
UnknownFeasibility of Telehealth Occupational Therapy for Behavioral Symptoms of Adults With Dementia: Randomized Controlled Trial.
Not available
S-EPMC10494967 | biostudies-literature
UnknownCOVID-19 Mortality Rates Among Nursing Home Residents Declined From March To November 2020.
Not available
S-EPMC8045482 | biostudies-literature
TranscriptomicsImpact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST
We performed RNA-seq and ChIP-seq on clones of human cell lines carrying an inducible XIST transgene on 1p, 8p, or 12q to study the effects of allelic silencing in cis Total gene expression and allelic changes were examined in HT1080 clones carrying an inducible XIST transgene on 1p, 8p, or 12q afte...
ORGANISM(S): Homo sapiens 
2015-09-02 | E-GEOD-68109 | biostudies-arrayexpress
UnknownAvelumab, an Anti-Programmed Death-Ligand 1 Antibody, In Patients With Refractory Metastatic Urothelial Carcinoma: Results From a Multicenter, Phase Ib Study.
Not available
S-EPMC5493051 | biostudies-literature
UnknownChromatin binding by HORMAD proteins regulates meiotic recombination initiation
Not available
S-SCDT-10_1038-S44318-024-00034-3 | biostudies-other
TranscriptomicsTranscriptomic (RNA-seq) analysis of wild-type and Nolz1-/- (Zfp503) mutant striatal tissue reveals altered expression of several genes involved in striatal projection neuron specification.
Midbrain dopaminergic (DA) axons make long longitudinal projections towards target areas in the forebrain, including the striatum. After demonstrating a striatal specific requirement of transcriptional regulator Nolz1 (Zfp503) in regulating DA axon guidance and innervation, we performed RNA-seq anal...
ORGANISM(S): Mus musculus 
2020-05-12 | E-MTAB-8240 | biostudies-arrayexpress
TranscriptomicsAdditional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array
Background: Measurement of genome-wide DNA methylation (DNAm) has become an important avenue for investigating potentially functional changes in various pathological conditions. Illumina Infinium is a relatively inexpensive and user-friendly DNAm microarray platform used by many researchers to measu...
ORGANISM(S): Homo sapiens 
2013-03-04 | E-GEOD-42409 | biostudies-arrayexpress
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