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UnknownDose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial.
Not available
S-EPMC3816958 | biostudies-literature
TranscriptomicsAnalysis of bacterial and macrophage transcripts in ISRE-positive and negative infected macrophages
To identify bacterial transcripts that may be associated with type I IFN production in Salmonella enterica subsp typhimurium (SL1344) infected macrophages we transformed macrophages with an ISRE-GFP reporter construct and sorted separate populations of GFP positive and GFP negative infected macropha...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65531 | biostudies-arrayexpress
TranscriptomicsSingle cell analysis of macrophages exposed to beads coated with LPS from Salmonella enterica subsp. typhimurium
We present a detailed single cell analysis of the macrophage response to LPS from Salmonella enterica. By combining single cell transcriptional analysis, fluorescently labeled, LPS-coated beads, and cytometry we are able to distinguish the responses of macrophages that have internalized LPS-coated ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65529 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq analysis of the macrophage response to Salmonella enterica subsp. Typhimurium (SL1344) exposure
A time course of the macrophage response to Salmonella exposure analyzing the effects of input cell number as a control for single cell studies Mouse macrophages were exposed to Salmonella enterica for different lengths of time. Libraries were constructed using either approximately 500,00 macrophag...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65530 | biostudies-arrayexpress
TranscriptomicsSingle cell time course of macrophages exposed to Salmonella enterica subsp. typhimurium
We present a detailed single cell time course of the macrophage response to Salmonella infection. By combining phenotypic fluorescent labels with single cell expression analysis we are able to identify gene modules associated with bacterial exposure and bacterial infection. We also identify other ...
ORGANISM(S): Mus musculus 
2015-09-07 | E-GEOD-65528 | biostudies-arrayexpress
UnknownTrends in Aortic Stenosis Mortality Among Older Adults in the United States from 1999 to 2020.
Not available
S-EPMC12693473 | biostudies-literature
TranscriptomicsInfluence of Fatty Acid Diets on Gene Expression in Rat Mammary Epithelial Cells
Background: This study examines the impact of dietary fatty acids on regulation of gene expression in the mammary epithelial cells before and during puberty. Methods: The diets primarily consisted of n-9 monounsaturated fatty acids (olive oil), n-6 polyunsaturated fatty acids (safflower), saturated ...
ORGANISM(S): Rattus norvegicus 
2009-04-01 | E-GEOD-14933 | biostudies-arrayexpress
TranscriptomicsLactobacillus johnsonii NCC comparative genomics with L. iatae
Whole genome DNA microarray designed for the probiotic L. johnsonii strain NCC533 was used for comparative genomic hybridization (CGH) of L. johnsonii ATCC 33200T, L. johnsonii BL261, L. gasseri ATCC 33323T and L. iatae BL263 (CECT 7394T). In these experiments, the fluorescence ratio distributions o...
ORGANISM(S): Lactobacillus johnsonii 
2010-11-24 | E-GEOD-21627 | biostudies-arrayexpress
TranscriptomicsGene expression of whole hippocampus 24hr post-injury in rat
Traumatic brain injury (TBI) alters and dysregulates the expression of thousands of genes in the brain. Since some of the most common problems in TBI patients are learning and memory deficits, we are studying the effects of TBI on the hippocampus, a region of the brain which is essential for learnin...
ORGANISM(S): Rattus norvegicus 
2015-01-08 | E-GEOD-59645 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and hog1 Candida albicans subjected to environmental stresses that are known to activate the Hog1 Stress-activated Protein Kinase
Based on studies in S. pombe (Chen et al., 2003), we predicted that conditions which activate C. albicans Hog1 would result in the induction of a common set of genes that are regulated by this SAPK (Smith et al., 2004). Hence in this study we compared the global transcriptional responses of wild-typ...
ORGANISM(S): Candida albicans 
2007-07-05 | E-MEXP-1134 | biostudies-arrayexpress
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