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TranscriptomicsMiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action at target tissu...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17058 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brown adipose tissue in a glycerol kinase (Gyk) knockout mouse model to define GyKs role in insulin resistance
Glycerol kinase (GK) is at the interface of fat and carbohydrate metabolism and has been implicated in insulin resistance and type 2 diabetes mellitus (T2DM). To define GK's role in insulin resistance, we examined gene expression in brown adipose tissue in a glycerol kinase (Gyk) knockout (KO) mouse...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4656 | biostudies-arrayexpress
TranscriptomicsExpression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
This SuperSeries is composed of the following subset Series: GSE17058: MiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes GSE17059: Gene expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes Refer to individual Series
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17060 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of congenic rat strains
Expression analysis was carried out in Goto-Kakizaki (GK), Brown Norway (BN) and 24 derived congenic strains using the Illumina RatRef-12 microarray. Each congenic line contains an introgression of a single fragment of the GK strain in the background of the BN recipient strain or vice versa. The res...
ORGANISM(S): Rattus norvegicus 
2014-01-20 | E-MTAB-1048 | biostudies-arrayexpress
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS382 | MetaboLights
TranscriptomicsHepatic gene expression profile in persimmon peel extract administrated GK rat
Persimmon (Diospyros kaki L. f.) is a most popular fruit in Asian countries but its peels are totally wasted despite of containing a plenty of antioxidants such as carotenoids and polyphenols. We prepared a fat-soluble extract from a persimmon peel (PP) fraction and fed type 2 diabetic Goto-Kakizak...
ORGANISM(S): Rattus norvegicus 
2011-03-17 | E-GEOD-21417 | biostudies-arrayexpress
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS390 | MetaboLights
MetabolomicsA metabolomic study of adipose tissue in mice with a disruption of the circadian system

Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can vary dramatically between meals and accor...

2017-10-27 | MTBLS380 | MetaboLights
TranscriptomicsTranscription profiling of rat to investigate effects of hyperglycaemi and genetic background on gene expression
Effects of hyperglycaemia and genetic background differences on renal gene expression
ORGANISM(S): Rattus norvegicus 
2008-08-09 | E-MEXP-1195 | biostudies-arrayexpress
TranscriptomicsSmall RNA-seq from ENCODE/Cold Spring Harbor Lab
This data was generated by ENCODE. If you have questions about the data, contact the submitting laboratory directly (Jonathan Preall jpreall@cshl.edu (Generation 0 Data from Hannon Lab), Carrie Davis davisc@cshl.edu (experimental), Alex Dobin dobin@cshl.edu (computational), Wei Lin wlin@cshl.edu (co...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-24565 | biostudies-arrayexpress
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