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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
ProteomicsMulti tissue proteomic analysis of cold exposure
This study explored the proteomic basis of cold adaptation, quantifying 11,394 proteins across 6 metabolic tissues and plasma. Systems level analysis revealed an enrichment for proteins involved in metabolism. In brown adipose tissue (BAT), cold adaptation was associated with enhanced glucose utilis...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-22 | PXD055965 | Pride
White adipose Mouse Brown adipose Liver Muscle 
TranscriptomicsGene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity (Exiqon)
Adipose tissue abundance relies partly on the factors that regulate adipogenesis, i.e. proliferation and differentiation of adipocytes. While the transcriptional program that initiates adipogenesis is well-known, the importance of microRNAs in adipogenesis is less well studied. We thus set out to in...
ORGANISM(S): Mus musculus 
2011-05-31 | E-GEOD-27912 | biostudies-arrayexpress
MetabolomicsRapid UHPLC-MS metabolite profiling and phenotypic assays reveal genotypic impacts of nitrogen supplementation in oats
INTRODUCTION: Oats (Avena sativa L.) are a whole grain cereal recognised for their health benefits and which are cultivated largely in temperate regions providing both a source of food for humans and animals, as well as being used in cosmetics and as a potential treatment for a number of...
2020-06-11 | MTBLS804 | MetaboLights
ProteomicsImpaired adipose-neuronal crosstalk in obesity
Label-free LC-MS/MS was used to characterise and quantify the secretory profiles of murine perivascular adipose tissue, canonical white adipose tissue, and brown adipose tissue.
ORGANISM(S): Mus musculus (Mouse) 
2022-11-15 | PXD031271 | Pride
Mouse Adipose tissue Label-free quantification 
UnknownLenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Not available
S-EPMC4067945 | biostudies-literature
UnknownExosomal formulation of anthocyanidins against multiple cancer types.
Not available
S-EPMC5837866 | biostudies-literature
MetabolomicsAssessing the impact of nitrogen supplementation in oats across multiple growth locations and years with targeted phenotyping and high-resolution metabolite profiling approaches
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
TranscriptomicsTranscriptome profiles of paternal testis and their offspring in response to gut microbiota dysbiosis using RNA sequencing analysis
Tissue samples harvested from conventionally-raised sire and their offspring or dysbiotic sire and their offspring were profiled for transcriptome changes using total RNA sequencing. Total RNA was extracted from four different tissue types: sire testis, F1 placenta (at E13.5 & E18.5), and F1 brain a...
ORGANISM(S): Mus musculus 
2023-11-13 | E-MTAB-10034 | biostudies-arrayexpress
UnknownVariation in food web reliance on green and brown energy pathways across ecosystem gradients.
Not available
S-EPMC12871965 | biostudies-literature
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