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TranscriptomicsFish oil/pectin temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis
We have demonstrated that fish oil/pectin (FO/P) diets protect against colon cancer compared to corn oil/cellulose (CO/C) by upregulating apoptosis and suppressing proliferation. To elucidate the mechanisms whereby FO/P diets induce apoptosis and suppress proliferation during the tumorigenic process...
ORGANISM(S): Rattus norvegicus 
2012-02-20 | E-GEOD-27266 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis sav mutants
Plants grown at high densities perceive a decrease in the red to far-red (R:FR) ratio of incoming light, resulting from absorption of red light by canopy leaves and reflection of far-red light from neighboring plants. These changes in light quality trigger a series of responses known collectively as...
ORGANISM(S): Arabidopsis thaliana 
2008-06-16 | E-GEOD-9816 | biostudies-arrayexpress
UnknownLongitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease.
Not available
S-EPMC11567864 | biostudies-literature
TranscriptomicsIsolation of a Novel Rat Neural Progenitor Clone that Expresses Dlx Family Transcription Factors and Gives Rise to Functional GABAergic Neurons in Culture
GABAergic interneurons are lost in conditions including epilepsy and CNS injury, but there are few culture models available to study their function. Towards the goal of obtaining renewable sources of GABAergic neurons, we used the molecular profile of a functionally-incomplete GABAergic precursor c...
ORGANISM(S): Rattus norvegicus 
2011-11-09 | E-GEOD-31635 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of rat ventricular myocytes cultured with recombinant human interleukin 6
Ventricular myocytes were isolated from adult male Sprague-Dawley rats (250-350g) by collagenase digestion. Cells were cultured with recombinant human interleukin 6 for six hours prior to isolation total RNA by RNeasy mini kit (Qiagen). RNA was amplified and labelled using the Illumina TotalPrep R...
ORGANISM(S): Rattus norvegicus 
2011-07-11 | E-MTAB-344 | biostudies-arrayexpress
TranscriptomicsCHSA transcriptional profiles
Transcriptional profiling of preangiogenic and angiogenic tumor nodules was conducted to identify genes that were differentially expressed during the transition from the preangiogenic to the angiogenic phenotype.
ORGANISM(S): Rattus norvegicus 
2013-01-24 | E-MEXP-3775 | biostudies-arrayexpress
UnknownAwareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN).
Not available
S-EPMC7206736 | biostudies-literature
GenomicsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

We conducted whole-genome sequencing of probands from several melanoma families, identifying one individual carrying a novel germline variant (c.G1075A, NM_000248.3; p.E318K, NP_000239.1; rs149617956) in the melanoma lineage-specific oncogene MITF. While the variant cosegregated with melanoma in ...

phs000419.v1.p1 | EGA
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
GenomicsBC
WTCCC1 project Breast cancer (BC) samples
EGAD00000000013 | EGA
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