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UnknownVegetation Formation in Staphylococcus Aureus Endocarditis Inversely Correlates With RNAIII and sarA Expression in Invasive Clonal Complex 5 Isolates.
Not available
S-EPMC9289551 | biostudies-literature
UnknownTranscription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci.
Not available
S-EPMC95583 | biostudies-literature
ProteomicsProteomic analysis of a filaggrin-deficient skin organoid model shows evidence of increased translation, keratinocyte-immune crosstalk and disordered axon guidance
Atopic eczema is an itchy inflammatory disorder characterised by skin barrier dysfunction. Loss-of-function mutations in the gene encoding filaggrin (FLG) are a major risk factor, but the mechanisms by which filaggrin haploinsufficiency leads to atopic inflammation remain incompletely understood. Sk...
ORGANISM(S): Homo sapiens (Human) 
2019-08-14 | PXD014875 | Pride
Atopic eczema Skin Human 
ProteomicsEMSY expression affects multiple components of skin barrier with relevance to atopic dermatitis
Atopic dermatitis (AD) is a heritable inflammatory disease, characterised by skin barrier dysfunction. Genome-wide association studies (GWAS) have identified molecular targets with relevance for drug development, but the strongest genetic association, FLG, has not yet been successfully targeted in a...
ORGANISM(S): Homo sapiens (Human) 
2019-06-24 | PXD014088 | Pride
Human Skin Proteomics Organotypic culture 
TranscriptomicsEffect of prenatal exposure to nicotine on kidney structure and gene expression in rats
Here, we investigated whether prenatal exposure to nicotine alters kidney glomerular mass and genome-wide gene expression profiles in two genetically distant strains of rats, namely spontaneously hypertensive rats (SHR) and Brown Norway (BN) rats. Nicotine or saline were administered to BN and SHR d...
ORGANISM(S): Rattus norvegicus 
2012-12-25 | E-GEOD-29677 | biostudies-arrayexpress
UnknownDifferentiation of Salmonella strains from the SARA, SARB and SARC reference collections by using three genes PCR-RFLP and the 2100 Agilent Bioanalyzer.
Not available
S-EPMC4127528 | biostudies-literature
TranscriptomicsPost-replicative formation of cohesion is required for repair and induced by a single DNA break
Sister chromatid cohesion, established during replication by the protein complex Cohesin, is essential for both chromosome segregation and double-strand break (DSB) repair. Normally cohesion formation is strictly limited to the S-phase of the cell cycle, but DSBs can trigger cohesion also after DNA ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-8270 | biostudies-arrayexpress
UnknownHypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease.
Not available
S-EPMC3326257 | biostudies-literature
TranscriptomicsTranscription profiling of human aortic smooth muscle cells exposed to hypoxia
Systemic arterial smooth muscle cells are exposed to a broad range of oxygen concentrations under physiological conditions. Hypoxia can modulate the proliferative response of smooth muscle cells leading to speculation about its role in vasculogenesis, vascular remodelling and the pathogenesis of ar...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4725 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the proteins co-purified with FLAG-HA Non-Stop FLAG-IPed from Drosophila melanogaster S2 cells
Protein Complexes Purification- Drosophila S2 cells were stably-transfected with pRmHa3-based inducible expression vectors to produce epitope-tagged Non-stop-2xFLAG-2xHA (Non-stop-FH). Cells stably transfected with empty vector served as negative control. Protein complexes containing Non-stop were p...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2018-07-17 | MSV000082625 | MassIVE
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