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ProteomicsHemi-methylated DNA regulates DNA methylation inheritance through allosteric control of H3 ubiquitylation by UHRF1
DNA methylation is a heritable chromatin modification essential to mammalian development that functions with histone post-translational modifications to regulate chromatin structure and gene expression programs. The epigenetic inheritance of DNA methylation requires the combined actions of DNMT1 and...
ORGANISM(S): Homo sapiens (Human) 
2016-08-25 | PXD003983 | Pride
Uhrf1 Ring e3 ligase Epigenetics Histone post-translational modifications Dna methylation Ubiquitin Histone h3 ubiquitylation 
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