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TranscriptomicsA Genomic Score Prognostic of Outcome in Trauma Patients
Physiological, anatomical, and clinical laboratory analytic scoring systems (APACHE, Injury Severity Score (ISS)) have been utilized, with limited success, to predict outcome following injury. We hypothesized that a peripheral blood leukocyte gene expression score could predict outcome, including mu...
ORGANISM(S): Homo sapiens 
2009-04-12 | E-GEOD-11375 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse leukocytes from blood and spleen obtained from animals treated with trauma-hemorrhage, burn injury or lipopolysaccharide (LPS)-infusion
gene expression profiles of leukocytes from blood (WBCs) and spleen harvested at an early (two hours) time point after injury or sham injury in mice subjected to trauma-hemorrhage, burn injury or lipopolysaccharide (LPS)-infusion at three experimental sites
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-2278 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human leukocytes or whole blood isolated from burn/trauma subjects using either buffy coat or PAXgene methods
#G017 Burn/Trauma Study. This is a Glue Grant Study comparison between gene expression analyses performed in eight trauma/burn subjects using either a buffy coat isolation of whole blood or using the PAXgene system
ORGANISM(S): Homo sapiens 
2007-07-28 | E-GEOD-1343 | biostudies-arrayexpress
UnknownMendelian etiologies identified with whole exome sequencing in cerebral palsy.
Not available
S-EPMC8862420 | biostudies-literature
UnknownIntegrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension.
Not available
S-EPMC11473243 | biostudies-literature
UnknownDrosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases.
Not available
S-EPMC8983390 | biostudies-literature
TranscriptomicsA genomic storm in critically injured humans
Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and show that the severe stress produce a global reprioritization affecting >80% of the cellular functions and pathways, a truly unexpected “ge...
ORGANISM(S): Homo sapiens 
2012-03-26 | E-GEOD-36809 | biostudies-arrayexpress
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