Sort   by:  
 Page size 
TranscriptomicsComprehensive gene expression analysis of Bruce-4 embryonic stem cells by SAGE
Mouse embryonic stem cells lines derived from different mouse strains show considerable variation concerning their culture conditions, gene targeting efficiency and germ line transmission capacity. To gain insight into the basis for this phenomenon, we generated a SAGE library of the C57BL/6 derived...
ORGANISM(S): Mus musculus 
2007-09-21 | E-GEOD-9078 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of male Fech mutant BALB/c mouse livers vs male control BALB/c livers
Comparison of gene expression in livers of male Fech mutant BALB/c mouse with livers of male control BALB/c
ORGANISM(S): Mus musculus 
2005-10-14 | E-MEXP-189 | biostudies-arrayexpress
ProteomicsDeciphering the architecture and interactome of the spliceosomal C complex using in vivo chemical crosslinking
We used in vivo PIR-based crosslinking to assess specific regions of interaction and protein structure of the spliceosomal C complex components hnRNPA1, A2/B1, and C, and the RALY protein. Our results indicate the interaction of proteins of the C complex via domains regions and conserved motifs, pos...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD023577 | Pride
Nuclear hnrnps Chemical cross-linking Splicing Rna-binding proteins Protein interaction reporter Interactome 
TranscriptomicsImpaired TLR3-mediated immune responses from macrophages of patients chronically infected with Hepatitis C virus
Hepatitis C virus (HCV) is the most common chronic blood-borne infection in the United States with the majority of patients becoming chronically infected and a subset (20%) progressing to cirrhosis and hepatocellular carcinoma. Individual variations in immune responses may help define successful res...
ORGANISM(S): Homo sapiens 
2013-03-05 | E-GEOD-40812 | biostudies-arrayexpress
TranscriptomicsGene microarray screening of RNA from bruce 4 ES cells
The sample is wild type male bruce 4 ES cells which has been used in core f to generate knockout mice. RNA samples from wild type male bruce 4 ES cells, which has been used in core f to generate knockout mice, were screened. Scraped cells, pre-plated and non-pre-plated trypsinized cells were compar...
ORGANISM(S): Mus musculus 
2011-06-14 | E-GEOD-29926 | biostudies-arrayexpress
UnknownBRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1.
Not available
S-EPMC4371995 | biostudies-literature
UnknownThe Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development.
Not available
S-EPMC543482 | biostudies-literature
UnknownBRUCE preserves genomic stability in the male germline of mice.
Not available
S-EPMC7370219 | biostudies-literature
ProteomicsThe C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion
Autosomal dominant polycystic kidney disease (ADPKD) is the most prevalent potentially lethal monogenic disorder. Mutations in the PKD1 gene, which encodes polycystin-1 (PC1), account for approximately 78% of cases. PC1 is a large 462-kDa protein that undergoes cleavage in its N and C-terminal domai...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-17 | PXD040210 | Pride
Metabolism Polycystin-1 (pc1) C-terminal tail (ctt) Autosomal dominant polycystic kidney disease (adpkd) Nicotinamide nucleotide transhydrogenase (nnt) Mitochondria 
UnknownNrdp1-mediated degradation of the gigantic IAP, BRUCE, is a novel pathway for triggering apoptosis.
Not available
S-EPMC380992 | biostudies-literature
Sort   by:  
 Page size