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GenomicsTranscriptome analysis of Drosophila melanogaster intestines upon knockdown of Tachykinin (Tk), the GPCR GulpR (CG32547), and bruchpilot (brp)
Transcriptome analysis of Drosophila melanogaster intestines upon knockdown of Tachykinin (Tk), the GPCR GulpR (CG32547), and bruchpilot (brp)
PRJNA1252059 | ENA
ProteomicsBlobby is a synaptic active zone assembly protein required for memory in Drosophila
At presynaptic active zones (AZs), scaffold proteins are critical for coordinating synaptic vesicle (SV) release and forming essential nanoarchitectures. However, regulatory principles steering AZ scaffold assembly, function, and plasticity remain insufficiently understood. We here identify a novel ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-03-17 | PXD058345 | Pride
Synapse Drosophila Bruchpilot 
TranscriptomicsTranscriptome analysis of Drosophila melanogaster intestines upon knockdown of Tachykinin (Tk), the GPCR GulpR (CG32547), and bruchpilot (brp)
Tk is a peptide hormone mainly expressed in the Drosophila brain and intestine. Gut-derived Tk is known to impact intestinal lipid metabolism and immunity. We used RNA-seq to determine the impact of Tk and the Tk regulators GulpR and brp on intestinal gene expression and further understand their rol...
ORGANISM(S): Drosophila melanogaster 
2025-12-05 | GSE294931 | GEO
UnknownQuantitative super-resolution imaging of Bruchpilot distinguishes active zone states.
Not available
S-EPMC4143948 | biostudies-literature
UnknownBruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila.
Not available
S-EPMC2759580 | biostudies-literature
UnknownComplexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix.
Not available
S-EPMC6400551 | biostudies-literature
UnknownThe Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles.
Not available
S-EPMC3747298 | biostudies-literature
ProteomicsActive zone plasticity drives presynaptic dephosphorylation in Drosophila
The function of the nervous system relies on tightly regulated, yet plastic synaptic vesicle release machinery at the presynaptic active zone. In Drosophila, a form of presynaptic active zone plasticity, Presynaptic Scaling, or PreScale, is executed by the ELKS-family scaffold protein Bruchpilot (BR...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-06-09 | PXD067034 | Pride
Bruchpilot (brp) Phospho-proteomics Drosophila Presynaptic scaling Prescale Proteomics 
UnknownAge-associated increase of the active zone protein Bruchpilot within the honeybee mushroom body.
Not available
S-EPMC5402947 | biostudies-literature
UnknownDrosophila Syd-1 Has RhoGAP Activity That Is Required for Presynaptic Clustering of Bruchpilot/ELKS but Not Neurexin-1.
Not available
S-EPMC5788532 | biostudies-literature
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