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Specific interactions of the genome with the nuclear lamina (NL) are thought to assist chromosome folding inside the nucleus and to contribute to the regulation of gene expression. High-resolution mapping has recently identified hundreds of large, sharply defined lamina-associated domains (LADs) in ...
ORGANISM(S): Drosophila melanogaster 
Specific interactions of the genome with the nuclear lamina (NL) are thought to assist chromosome folding inside the nucleus and to contribute to the regulation of gene expression. High-resolution mapping has recently identified hundreds of large, sharply defined lamina-associated domains (LADs) in ...
ORGANISM(S): Drosophila melanogaster 
The local protein composition of chromatin is important for the regulation of transcription and other functions. By integrative analysis of genome-wide binding maps of 53 broadly selected chromatin components in Drosophila cells, we show that the genome is segmented into five principal chromatin typ...
ORGANISM(S): Drosophila melanogaster 
The three-dimensional organization of chromosomes within the nucleus and its dynamics during differentiation are largely unknown. We present a genome-wide analysis of the interactions between chromatin and the nuclear lamina during differentiation of mouse embryonic stem cells (ESCs) into lineage-co...
ORGANISM(S): Mus musculus 
Exploratory study of copy number profiles of male breast cancer patients. The experiment contains 75 male breast cancer samples, analysed on a 135K whole genome CGH array
ORGANISM(S): Homo sapiens 
Human cell cultures (MCF7 and SY5Y) were subjected to volatile anesthetic gasses in an operation theater and monitored for full genome gene expression characteristics to learn more about the time dependent molecular mechanisms that occur during surgery and to find the implications that anesthetics m...
ORGANISM(S): Homo sapiens 
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