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ProteomicsIdentification of Native Cross-links in Bacillus subtilis Spore Coat Proteins
The resistance properties of the bacterial spores are partially due to spore surface proteins, ~30% of which are said to form an insoluble protein fraction. Previous research has also identified a group of spore coat proteins affected by spore maturation, which exhibit an increased level of inter pr...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) 
2021-01-09 | MSV000086681 | MassIVE
ProteomicsInduced homogenous sporulation by kinA-overexpression leads to altered Bacillus subtilis spore proteomes and spore properties
Summary To facilitate more accurate spore proteomic analysis, the current study focuses on inducing homogeneous sporulation by overexpressing kinA and assesses the effect of sporulation synchronization on spore resistance, structures, the germination behavior at single-spore level and the proteome. ...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) 
2020-04-28 | MSV000085346 | MassIVE
ProteomicsIntegrative analysis of proteome and transcriptome dynamics during Bacillus subtilis spore revival
Description Bacillus subtilis forms highly resistant, metabolically inactive spores upon nutrient limitation. These endospores pose challenges to the food and medical sectors. Spores reactivate their metabolism upon contact with germinants through germination and outgrowth, and then develop into ve...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) 
2020-04-02 | MSV000085217 | MassIVE
TranscriptomicsTime-resolved heat stress response of Saccharomyces cerevisiae
Whole-genome transcriptional response of S. cerevisiae to an increase in temperature from 28M-BM-0C to 41M-BM-0C under well-controlled conditions. Two subsequent phases of response with very different dynamics: a short term response for the first hour after the temperature increase and a long term ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-01 | E-GEOD-25503 | biostudies-arrayexpress
TranscriptomicsTime-series of transcriptome analysis of Bacillus subtilis response to 25 mM potassium acetate and 0.85 M-BM-5M CCCP
The advent of M-bM-^@M-^XomicsM-bM-^@M-^Y techniques bear significant potential for the assessment of the microbiological stability of foods. This requires the integration of molecular data with their implication for cellular physiology. Here we performed a comparative physiological and transcriptio...
ORGANISM(S): Bacillus subtilis 
2014-04-11 | E-GEOD-55051 | biostudies-arrayexpress
ProteomicsMolecular physiological characterization of a high heat resistant spore forming Bacillus subtilis food isolate
Bacterial endospores (spores) are among the most resistant living forms on earth. Spores of Bacillus subtilis A163 show extremely high resistance to wet heat compared to spores of laboratory strains. In this study, we found that spores of B. subtilis A163 were indeed very wet heat resistant and rele...
ORGANISM(S): Bacillus Subtilis 
2021-03-21 | MSV000087080 | MassIVE
ProteomicsHigh resolution time-lapse proteomic analysis of sporulation
Bacillus subtilis vegetative cells switch to sporulation upon nutrient limitation. To investigate the proteome changeover during sporulation, a time-lapse proteomic analysis was performed in a cell population that was induced to sporulate synchronously. Here, we are the first to comprehensively inve...
ORGANISM(S): Bacillus Subtilis 
2021-04-03 | MSV000087154 | MassIVE
ProteomicsDynamics of Germinosome Formation Interactions between GerD and Germinant Receptor Subunits in Bacillus cereus Spores
Spores of the bacterium Bacillus cereus can cause disease in humans due to contamination of raw materials for food manufacturing. These dormant, resistant spores can survive for years in the environment, but can germinate and grow when their surroundings become suitable, and spore germination protei...
ORGANISM(S): Bacillus Cereus (ncbitaxon:1396) 
2022-01-24 | MSV000088726 | MassIVE
MetabolomicsIntegrated multi-omics of feces, plasm aand urine can describe and differentiate pediatric active Crohn’s Disease from remission

Background

This study aimed to obtain a holistic view of remission in pediatric Crohn’s Disease (CD) by integrating six omics datasets from three anatomical compartments.


Methods

Patients with fecal calprotectin below 250 mg/kg were c...

2025-07-09 | MTBLS9877 | MetaboLights
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