In a collaboration between Welcome Trust Sanger Institute (WTSI), Royal Veterinary College (RVC) and King Abdullah University of Science and Technology (KAUST), we have sequenced, assembled and annotated the genome of Eimeria brunetti Houghton.
In the obese state, as adipose tissue expands, adipocytes become hypoxic and dysfunctional, leading to changes in the pattern of secreted proteins. To better understand the role of hypoxia in the mechanisms linked to obesity, we comparatively analyzed the secretome of differentiated 3T3-L1 adipocyte...
Protein O-GlcNAcylation is a fast-cycling and nutrient-sensitive post-translational modification (PTM) involved in several functions, including hepatic metabolsm. The substrate of O-GlcNAcylation is UDP-GlcNAc, the end-product of the hexosamine biosynthesis pathway that is initiated by glutamine. O-...
