Sort   by:  
 Page size 
TranscriptomicsThe RNA binding protein Arrest (Aret) regulates myofibril maturation in Drosophila flight muscle
In Drosophila, fibrillar flight muscles (IFMs) enable flight, while tubular muscles mediate other body movements. Here, we use RNA-sequencing and isoform-specific reporters to show that spalt major (salm) determines fibrillar muscle physiology by regulating transcription and alternative splicing of ...
ORGANISM(S): Drosophila melanogaster 
2014-12-23 | E-GEOD-63707 | biostudies-arrayexpress
TranscriptomicsComparative analysis of Bruno-3 gain of function in Drosophila larval muscles
Myotonic dystrophy type 1 (DM1) is a neuro-muscular disorder caused by CTG triplet expansion in the 3'-UTR of the DMPK gene. Mutated transcripts aggregate in muscle nuclei and increase CUGBP1 stability by a not-yet determined mechanism. To assess the involvement of CUGBP1 in DM1, we used Drosophila ...
ORGANISM(S): Drosophila melanogaster 
2017-03-24 | E-MTAB-3231 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins
The human malaria parasite Plasmodium falciparum employs intricate post-transcriptional regulatory mechanisms in different stages of its life cycle. Despite the importance of post-transcriptional regulation, key elements of these processes, namely RNA binding proteins (RBPs), are poorly characterize...
ORGANISM(S): Plasmodium falciparum 
2014-10-23 | E-GEOD-56329 | biostudies-arrayexpress
MetabolomicsUnique metabolism of different glucosinolates in larvae and adults of a leaf beetle specialised on Brassicaceae
Brassicaceae plants contain glucosinolates, which are hydrolysed by myrosinases to toxic products such as isothiocyanates and nitriles, acting as defences. Herbivores have evolved various detoxification strategies, which are reviewed here. Larvae of Phaedon cochleariae (Coleoptera: Chrysomelidae) me...
2022-11-11 | MTBLS3565 | MetaboLights
GenomicsAquarana catesbeiana isolate:Bruno
Aquarana catesbeiana isolate:Bruno Genome sequencing and assembly
PRJNA285814 | ENA
UnknownBruno protein contains an expanded RNA recognition motif.
Not available
S-EPMC4301712 | biostudies-literature
UnknownMultiple RNA binding domains of Bruno confer recognition of diverse binding sites for translational repression.
Not available
S-EPMC3360078 | biostudies-literature
UnknownSex-lethal is a target of Bruno-mediated translational repression in promoting the differentiation of stem cell progeny during Drosophila oogenesis.
Not available
S-EPMC1904479 | biostudies-literature
ProteomicsBruno 1 regulates cytoskeleton dynamics and a temporal splicing transition to promote myofibril assembly, growth and maturation in Drosophila flight muscle
Muscles undergo developmental transitions in gene expression and alternative splicing that are necessary to refine sarcomere structure and contractility. CUG-BP and ETR-3-like (CELF) family RNA binding proteins are important regulators of RNA processing during myogenesis that are misregulated in dis...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-03-08 | PXD043308 | Pride
Muscle development Drosophila Flight muscle Celf Bruno 1 
UnknownThe Drosophila Bruno paralogue Bru-3 specifically binds the EDEN translational repression element.
Not available
S-EPMC434433 | biostudies-literature
Sort   by:  
 Page size