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ProteomicsAn unprecedented binding mode of vitamin B12 in the predicted transporter BtuM
BtuM binds vitamin B12 (cyano-cobalamin) in an unprecedented way. Structural and spectroscopic data indicate that the unusual thiolate coordination allows for chemical modification of the substrate, which is decyanation of the compund. We use mass-spectrometry to show the loss of the 26 Da moiety wi...
ORGANISM(S): Thiobacillus denitrificans ATCC 25259 
2018-10-18 | PXD010024 | Pride
Btum Decyanation 
UnknownCysteine-mediated decyanation of vitamin B12 by the predicted membrane transporter BtuM.
Not available
S-EPMC6072759 | biostudies-literature
UnknownDiscovery of New Protein Targets of BPA Analogs and Derivatives Associated with Noncommunicable Diseases: A Virtual High-Throughput Screening.
Not available
S-EPMC7997610 | biostudies-literature
ProteomicsQuantitative proteomic analysis of fresh-frozen human breast tissue and tumor samples using microLC-SWATH-MS
Future improvements in the field of breast cancer prevention, diagnosis and treatment require deeper knowledge and better understanding of the molecular processes and signaling pathways that lead to the transformation of normal cells to cancer ones and the disease progression. Quantitative proteome ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD008408 | Pride
Breast tissue Fresh frozen Breast tumor Microlc Swath-ms Quantitative proteomics 
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