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Future improvements in the field of breast cancer prevention, diagnosis and treatment require deeper knowledge and better understanding of the molecular processes and signaling pathways that lead to the transformation of normal cells to cancer ones and the disease progression. Quantitative proteome ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD008408 | Pride
We investigated the changes in the peptide profile of pasteurized milk during its shelf life to identify storage-dependent markers. Accordingly, two independent storage experiments were performed and their peptide profiles were recorded with microLC–timsTOF Pro-MS/MS.
ORGANISM(S): Bos taurus (Bovine) 
2026-01-19 | PXD068410 | Pride
This study analyzed the impact of proteolysis by Streptococcus thermophilus (ST), Lactobacillus delbrueckii subsp. bulgaricus (LB), and endogenous milk enzymes on peptide formation during lactic acid fermentation. For this, peptide profiles of bovine milk fermented with single or mixed culture of ST...
ORGANISM(S): Bos taurus (Bovine) 
2026-07-07 | PXD065496 | Pride
This study optimized identification rate and reproducibility of an untargeted diaPASEF approach for quantitative peptide profiling of hydrolyzed infant formula. For this, the impact of variable window widths as well as major acquisition parameters, such as the precursor coverage, number of diaPASEF ...
ORGANISM(S): Bos taurus (Bovine) 
2026-03-05 | PXD066057 | Pride
The investigation focused on the impact of software settings Bovine alpha-lactalbumin was used as a model protein due to its relatively small size, allowing for detailed tracking of any resulting changes. Furthermore, the reproducibility of results was investigated based on 18 measurements of the sa...
ORGANISM(S): Bos taurus (Bovine) 
2024-09-23 | PXD050363 | Pride
Imatinib is a tyrosine kinase inhibitor (TKI) indicated for chronic myeloid leukemia (CML) and other cancers. It is metabolized by CYP2C8 and CYP3A into a major active metabolite N-desmethyl-imatinib. The purpose of the study was to determine in vitro the influence of CYP2C8 and CYP3A phenotypes, su...
ORGANISM(S): Homo sapiens (Human) 
2025-12-13 | PXD066482 | Pride
Metabolic dysfunction-associated steatotic liver disease (MASLD) is estimated to affect approximately 30% of adults worldwide. The progressive form of MASLD, namely metabolic-dysfunction steatohepatitis (MASH), is a leading cause of chronic liver disease. MASH is marked by hepatocellular fat accumul...
ORGANISM(S): Homo sapiens (Human) 
2025-12-12 | PXD071083 | Pride
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