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MetabolomicsEffects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian morphology. Gut microbiota dysbiosis and metabolite are associated with PCOS clinical parameters. Yulin Tong Bu formula (YLT...

2023-02-02 | MTBLS6736 | MetaboLights
TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
TranscriptomicsDynamic binding of RBPJ is determined by Notch signalling status
Notch signalling plays crucial roles in mediating cell fate choices in all metazoans largely by specifying the transcriptional output of one cell in response to a neighbouring cell. The DNA-binding protein RBPJ is the principle effector of this pathway in mammals and together with the transcription ...
ORGANISM(S): Mus musculus 
2013-05-13 | E-GEOD-37184 | biostudies-arrayexpress
UnknownA Mononuclear Carboxylate-Rich Oxoiron(IV) Complex: a Structural and Functional Mimic of TauD Intermediate 'J'
Not available
S-EPMC3528080 | biostudies-literature
ProteomicsSaw-scaled viper, Echis carinatus sochureki, venomics
we used a combination of bottom-up (BU) and top-down (TD) proteomics approaches to identify and characterize venom protein compositions of Echis carinatus sochureki (ECS) from three different Iranian populations.
ORGANISM(S): Echis carinatus sochureki 
2021-01-29 | PXD021183 | Pride
Iran Saw-scaled viper Echis carinatus sochureki Venomics 
UnknownJ-shaped association between fasting blood glucose levels and COVID-19 severity in patients without diabetes.
Not available
S-EPMC7445136 | biostudies-literature
UnknownExperiences of patients with cervical cancer undergoing concurrent chemoradiation therapy at the Korle-Bu teaching hospital in Ghana: an explorative qualitative study.
Not available
S-EPMC12512744 | biostudies-literature
TranscriptomicsA conserved two-component signal transduction system controls the response to phosphate starvation in Bifidobacterium breve UCC2003
This work reports on the identification and molecular characterization of a two-component regulatory system (2CRS), encoded by phoRP in Bifidobacterium breve UCC2003, which controls the response to phosphate (Pi) starvation. The response regulator PhoP was shown to bind to the promoter region of pst...
ORGANISM(S): Bifidobacterium breve UCC2003 
2012-09-06 | E-GEOD-34983 | biostudies-arrayexpress
UnknownCirculation of hepatitis delta virus and occult hepatitis B virus infection amongst HIV/HBV co-infected patients in Korle-Bu, Ghana.
Not available
S-EPMC7790253 | biostudies-literature
UnknownFunctional Characterization of the Lactolisterin BU Gene Cluster of Lactococcus lactis subsp. lactis BGBU1-4.
Not available
S-EPMC6249370 | biostudies-literature
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