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ProteomicsInvestigating the Antifibrotic Effects of β-Citronellol on a TGF-β1-stimulated LX-2 Hepatic Stellate Cell Model
Liver fibrosis, a consequence of chronic liver damage or inflammation, is characterized by the excessive buildup of extracellular matrix components. This progressive condition significantly raises the risk of severe liver diseases like cirrhosis and hepatocellular carcinoma. The lack of approved the...
ORGANISM(S): Homo sapiens (Human) 
2024-08-06 | PXD052806 | Pride
Hepatic stellate cell Citrus hystrix dc. Liver fibrosis Β-citronellol Proteomic analysis Lc-ms/ms 
Proteomics7-Octenoic Acid Exerts Anti-Fibrotic Effects on TGF-β1-Activated Hepatic Stellate Cells: Insights from Proteomic Analysis
Liver fibrosis represents the liver’s adaptive response to sustained inflammation triggered by diverse insults such as dietary factors and infectious agents. Although early-stage fibrosis can be reversible, unchecked progression often leads to cirrhosis and hepatocellular carcinoma. Therapeutic opti...
ORGANISM(S): Homo sapiens (Human) 
2025-11-10 | PXD063183 | Pride
Hepatic stellate cell 7-octenoic acid Moringa oleifera lam. Liver fibrosis Proteomics 
ProteomicsIn Vitro Investigation of The Anti-Fibrotic Potential of 1-Phenyl-2-Pentanol, Identified from Moringa Oleifera Lam. on Hepatic Stellate Cells
Liver fibrosis, characterized by excessive extracellular matrix deposition, is driven by activated hepatic stellate cells (HSCs). Due to the limited availability of anti-fibrotic drugs, research con-tinues to explore potential therapeutic agents. Moringa oleifera Lam. (MO), known for its various bio...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD052809 | Pride
Hepatic stellate cell Liver fibrosis Moringa oleifera lam. Molecular docking analysis Proteomics 1-phenyl-2-pentanol Lc-ms/ms 
ProteomicsProteomic profiling of oleamide-mediated polarization in a primary human monocyte-derived tumor-associated macrophages model: a functional analysis
To investigate the effect of oleamide on tumor-associated macrophages (TAMs) polarization.
ORGANISM(S): Homo sapiens (Human) 
2024-08-25 | PXD043461 | Pride
Oleamide Tumor-associated macrophages Polarization Proteomic Tam 
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