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ProteomicsFBXO9 in Murine Inversion 16 AML
The hematopoietic system is maintained throughout life by hematopoietic stem cells that are capable of differentiation to all hematopoietic lineages. An intimate balance between self-renewal, differentiation, and quiescence is required to maintain hematopoiesis. Disruption of this balance can result...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-27 | PXD014387 | Pride
Fbxo9 aml inv(16) spleen 
ProteomicsProtein landscape in acute myeloid leukemia reveals proteins susceptible for drug discovery
Acute myeloid leukemia (AML) is a devastating cancer affecting the hematopoietic system. Although this disease represents only 35% of diagnosed leukemias, it accounts for nearly 50% of leukemia-related deaths, making it the leading cause of leukemia-related mortality. Although many AML initiating mu...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-20 | PXD025628 | Pride
Acute myeloid leukemia Aml 
ProteomicsUBR5 in B cell development TMT
Coordination of a number of molecular mechanisms including transcription, alternative splicing, and class switch recombination are required to facilitate development, activation, and survival of B cells. Disruption of these pathways can result in malignant transformation. Recently, next generation s...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-19 | PXD014307 | Pride
Tmt ubr5 bcells spleen mouse 
ProteomicsUbiquitin E3 ligase FBXO21 regulates cytokine mediated signaling pathways, but is dispensable for steady-state hematopoiesis
Hematopoietic cell fate decisions such as self-renewal and differentiation are highly regulated through multiple molecular pathways. One pathway, the ubiquitin proteasome system (UPS), controls protein levels by tagging them with polyubiquitin chains and promoting their degradation through the prote...
ORGANISM(S): Mus musculus (Mouse) 
2022-11-11 | PXD035283 | Pride
Fbox Hematopoietic stem cell Ubiquitin e3 ligase 
UnknownGenome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Not available
S-EPMC4549775 | biostudies-literature
UnknownAVERT2 (a very early rehabilitation trial, a very effective reproductive trigger): retrospective observational analysis of the number of babies born to trial staff.
Not available
S-EPMC4676118 | biostudies-literature
UnknownExploring threats to generalisability in a large international rehabilitation trial (AVERT).
Not available
S-EPMC4550737 | biostudies-literature
UnknownEffect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.
Not available
S-EPMC6289056 | biostudies-literature
UnknownEffect of Aspirin on Disability-free Survival in the Healthy Elderly.
Not available
S-EPMC6426126 | biostudies-literature
UnknownEffect of Aspirin on All-Cause Mortality in the Healthy Elderly.
Not available
S-EPMC6433466 | biostudies-literature
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