Sort   by:  
 Page size 
UnknownDeficiency in the LIM-only protein Fhl2 impairs skin wound healing.
Not available
S-EPMC2064120 | biostudies-literature
GenomicsRCC_HTA2.0_Buettner2022
GeneChip HTA 2.0 data of primary renal cell carcinoma (RCC) related to Buettner et al, Genome Med 2022. Microarrays were normalized individually using the SCAN method from the R package SCAN.UPC (version 2.26.0, R version 3.6.1). Probe sets were summarized on the Entrez GeneID level using the annota...
EGAD00010002353 | EGA
Proteomics"Effects of cigarette smoke, cessation and switching to a modified risk tobacco product on the liver in Apoe-/- mice -- a systems toxicology analysis"
"Liver represents one of the most important organs involved in the elimination of xenobiotic and potentially toxic substances. Cigarette smoke (CS) contains more than 7000 chemicals, among which compounds that exert biological effects and cause smoking-related diseases. Although CS is not directly h...
ORGANISM(S): Mus musculus (Mouse) 
2016-12-22 | PXD002925 | Pride
Cigarette smoke "mouse Modified risk tobacco product Liver" 
TranscriptomicsTranscription profiling of rat liver samples from animals fed lard, olive oil, coconut fat, or cod liver oil diets
High fat diet (HF) rodent models have contributed significantly to the dissection of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different studies. Here, we have analyzed gene expression patterns in livers of animals fed with different HF wit...
ORGANISM(S): Rattus norvegicus 
2007-10-10 | E-GEOD-3512 | biostudies-arrayexpress
Transcriptomics28d Rat Inhalation Study
We have performed a 28 days rat inhalation study according to the OECD TG 412 by exposing rats for 28 days to filtered air (sham), or to a low, medium, or high concentration of mainstream (MS) cigarette smoke (CS) from the Reference cigarette 3R4F in addition to MS CS from a prototypic modified risk...
ORGANISM(S): Rattus norvegicus 
2014-05-30 | E-MTAB-1842 | biostudies-arrayexpress
ProteomicsUse of Apoe−/− Mice in an 8-Month Systems Toxicology Inhalation/Cessation Study to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared with Conventional Cigarettes
Cigarette smoking is a major risk factor for the development and progression of cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD), so modified risk tobacco products (MRTPs) are being developed to reduce smoking-related health risks. The present study investigated the hall...
ORGANISM(S): Mus musculus (Mouse) 
2015-11-30 | PXD002530 | Pride
Mouse Lung Cigarette smoke Modified risk tobacco product 
UnknownProteomic analysis of pleomorphic dermal sarcoma reveals a fibroblastic cell of origin and distinct immune evasion mechanisms.
Not available
S-EPMC11143252 | biostudies-literature
ProteomicsProteomic analysis of pleomorphic dermal sarcoma
In this study, we aimed to unravel the molecular underpinnings of pleomorphic dermal sarcomas (PDS), rare skin tumors often seen in sun-exposed regions. Using mass spectrometry, we examined proteomic profiles of 20 samples of normal healthy skin tissue (SNT), 27 malignant melanomas (MM), 20 cutaneou...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD046388 | Pride
Immune evasion Protein analysis Fibroblastic lineage Pleomorphic dermal sarcoma (pds) 
ProteomicsQuantitative secretomics during cardiomyogenic differentiation of human pluripotent stem cells
Cardiovascular diseases are a major cause of life-threatening burden around the world. The heart has a very low regeneration capacity and donor organs for transplantation are scarce. Therefore regeneration of lost myocardium with stem cell-derived cardiomyocytes (CMs) provides an attractive strategy...
ORGANISM(S): Homo sapiens (Human) 
2018-06-20 | PXD008554 | Pride
Hescs Cardiomyogenesis Secretomics Hipscs Lc-ms/ms 
UnknownLung inflammatory effects, tumorigenesis, and emphysema development in a long-term inhalation study with cigarette mainstream smoke in mice.
Not available
S-EPMC3551427 | biostudies-literature
Sort   by:  
 Page size