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In times of cellular stress, such as during virus infections, the integrated stress response (ISR) blocks translation initiation through phosphorylation of the essential translation initiation factor eIF2. Phosphorylated eIF2 (p-eIF2) sequesters the eIF2-specific guanidine exchange factor (GEF) eIF2...
ORGANISM(S): Homo sapiens (Human) 
2020-07-24 | PXD011879 | Pride
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