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UnknownTherapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis.
Not available
S-EPMC7398876 | biostudies-literature
ProteomicsCCR1 inhibition sensitizes multiple myeloma cells to glucocorticoid therapy
One of the cornerstone drugs in the treatment of multiple myeloma (MM) are glucocorticoids. Because MM cells hijack the bone marrow microenvironment to obtain growth and survival signals, resistance to glucocorticoid-induced apoptosis emerges, yet, the underlying mechanisms remain poorly characteriz...
ORGANISM(S): Homo sapiens (Human) 
2025-06-18 | PXD055337 | Pride
Myeloma Glucocorticoids Dexamethasone Ccr1 Bx471 
UnknownA chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.
Not available
S-EPMC150841 | biostudies-literature
TranscriptomicsCCR1 deficiency promotes adipocyte browning via cAMP/PKA/CREB signaling to suppress obesity in mice
Enhancing brown adipose tissue (BAT) activity and browning of white adipose tissue (WAT) are promising novel strategies for combating obesity and insulin resistance. Previously, we identified CCR1 as a key regulator of non-alcoholic steatosis. Here, we present evidence of the physiological role of C...
ORGANISM(S): Mus musculus 
2026-08-12 | GSE274417 | GEO
UnknownIdentifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, β-arrestin translocation and chemotaxis assays.
Not available
S-EPMC4253460 | biostudies-literature
UnknownEosinophil-derived chemokine (hCCL15/23, mCCL6) interacts with CCR1 to promote eosinophilic airway inflammation.
Not available
S-EPMC7914252 | biostudies-literature
UnknownDSE regulates the malignant characters of hepatocellular carcinoma cells by modulating CCL5/CCR1 axis.
Not available
S-EPMC6405965 | biostudies-literature
TranscriptomicsStress Promotes Lung Metastasis in Breast Cancer by Altering Neutrophil Differentiation
Mental stress is widely recognized as a significant risk factor for breast cancer, exerting detrimental effects on both progression and prognosis. Herein, we investigated the role of stress in regulating breast cancer metastasis. In genetically engineered and transplantation breast cancer mouse mode...
ORGANISM(S): Mus musculus 
2025-09-14 | GSE297920 | GEO
GenomicsCCR1 deficiency promotes adipocyte browning via cAMP/PKA/CREB signaling to suppress obesity in mice
CCR1 deficiency promotes adipocyte browning via cAMP/PKA/CREB signaling to suppress obesity in mice
PRJNA1146384 | ENA
UnknownSingle-cell RNA sequencing identifies ZBP1-dependent mechanisms in OSCC progression.
Not available
S-EPMC12749536 | biostudies-literature
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