Glucocorticoids

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Unknown (3713)
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gut metagenome (1)
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Disease

Lung cancer (2)
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High bone mineral density (1)
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Acute leukemia (1)
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COVID-19 (1)
Cachexia (1)
Chronic bronchitis (1)
Chronic obstructive pulmonary disease (1)
Lung carcinoma (1)
Multiple myeloma (1)
Obesity (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (44)
Shotgun proteomics (25)
Bottom-up proteomics (9)
Mass spectrometry (6)
Data-independent acquisition (5)
Affinity purification coupled with mass spectrometry proteomics (4)
Data-dependent acquisition (4)
SWATH MS (3)
Illumina HiSeq 2000 (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Gel-based experiment (2)
Mass spectrometry assay (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (8)
Illumina HiSeq 2500 (7)
Illumina HiSeq 4000 (4)
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Impact (2)
Q Exactive (2)
Exactive (Thermo Scientific) (2)
Liquid Chromatography MS - positive - reverse phase (2)
Liquid Chromatography MS - negative - reverse phase (2)
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Gas Chromatography MS - (1)

Publication Date

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2013 (41)
2014 (36)
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2020 (34)
2010 (32)
2008 (32)
2017 (31)
2012 (31)
2018 (27)
2009 (22)
2016 (10)
2006 (9)
2005 (8)
2007 (8)
2004 (1)

CHEBI ID

CHEBI:17650 (3)
CHEBI:132991 (2)
CHEBI:73027 (2)
CHEBI:72736 (2)
CHEBI:8087 (2)
CHEBI:68434 (2)
CHEBI:133185 (2)
CHEBI:27781 (2)
CHEBI:36206 (2)
CHEBI:70959 (2)
CHEBI:82965 (2)
CHEBI:78600 (2)
CHEBI:84838 (2)
CHEBI:16070 (2)
CHEBI:17992 (2)
CHEBI:73040 (2)
CHEBI:73039 (2)
CHEBI:73061 (2)
CHEBI:27997 (2)
CHEBI:30805 (2)
CHEBI:86255 (2)
CHEBI:29019 (2)
CHEBI:48430 (2)
CHEBI:73074 (2)
CHEBI:74750 (2)
CHEBI:15903 (2)
CHEBI:16680 (2)
CHEBI:72723 (2)
CHEBI:28867 (2)
CHEBI:16750 (2)

Metabolite Name

Tridecanoylglycine (3)
2-Methylglutaric acid (3)
N-Decanoylglycine (3)
N-Undecanoylglycine (3)
Tetradecanedioic acid (3)
Hexadecanedioic acid (3)
Azelaic acid (3)
(+)-Prosopinine (2)
1,8-Dimethylnaphthalene (2)
Calcium Gluceptate (2)
O-Desmethylnaproxen (2)
Tetrahydroharmol (2)
2-Hydroxyhexadecanoylcarnitine (2)
Vulgarole (2)
Tromethamine (2)
Deoxycorticosterone (2)
Hepoxilin A3 (2)
Cycluron (2)
Glutamyltryptophan (2)
Ginsenoside Rg5 (2)
Pitheduloside A (2)
LysoPI(16:0/0:0) (2)
Sulfolithocholylglycine (2)
Armillane (2)
N-Palmitoyl Methionine (2)
N-Linoleoyl Valine (2)
Insignin A (2)
N-Oleoyl Alanine (2)
Idebenone (2)
2-Hydroxyenterodiol (2)

First Public Date

2014 (104)
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2026 (50)
2023 (47)
2022 (44)
2019 (41)
2020 (33)
2015 (29)
2017 (26)
2018 (24)
2013 (7)
2016 (6)

Modelling Approach

Ordinary differential equation model (1)

Study status

Recruiting (1)

Lab affiliation

Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, Munich, Germany (2)
Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, München, Germany, Feodor-Lynen-Straße 25, 81377 München (2)
Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Division of Infection Medicine, Lund, Sweden (2)
1 VIB-UGent Center for Medical Biotechnology, B9052 Ghent, Belgium; 2 Department of Biomolecular Medicine, Ghent University, B9052 Ghent, Belgium. (1)
1Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, München, Germany, Feodor-Lynen-Strasse 25, 81377 München (1)
1VIB Center for Medical Biotechnology (CMB), Ghent, 2Belgium Department of Biomolecular Medicine, Ghent University, Ghent, Belgium, 3Cancer Research Institute Ghent (CRIG), Ghent, Belgium. (1)
AstraZeneca (1)
Biozentrum, University of Basel, Switzerland (1)
Center of Neurogenomics and Cognitive Research (CNCR), Department of Molecular and Cellular Neurobiology, Vrije Universiteit, Amsterdam, Netherlands (1)
Copenhagen University (1)
Department of Biochemistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB T6G 2H7, Canada (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany (1)
Department of Pediatrics, the Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an , China (1)
Department of Pharmacy, Pharmaceutical Biology, Saarland University, Germany (1)
Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medical and Health Sciences. University of Manchester, UK. (1)
Head of Bioanalytics Group, Department of Environmental Toxicology (Utox), Eawag – Swiss Federal Institute of Aquatic Science and Technology, 8600 Duebendorf, Switzerland (1)
Institute for the Animal Production System in the Mediterranean Environment, National Research Council, 80055 Portici (Naples), Italy (1)
Instituto de Investigaciones Sanitarias de Santiago de Compostela (1)
Ludwig-Maximilians-Universität München, Department of Physiological Genomics - BioMedical Center BMC Großhaderner Str. 9 D-82152 Planegg-Martinsried (1)
Lymphoid Malignancies Branch Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda, Maryland (1)
Mass Spectrometry & Proteomics Core Facility (MSPCF) Institute for Research in Biomedicine (IRB Barcelona) Barcelona Institute of Science and Technology (BIST) C/ Baldiri Reixac, 10-12 08028 Barcelona - Spain. (1)
Mass spectrometry/Proteomics Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, 44801 Bochum, Germany; 44801 Bochum, Germany (1)
National Jewish Health (1)
Neuroinflammation and Mucosal Immunology Max Planck Institute of Biochemistry Am Klopferspitz 18 82152 Martinsried Germany (1)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen (1)
Pablo Menéndez, ICREA Research Professor Stem cell biology, developmental leukemia & immunotherapy Lab Josep Carreras Leukaemia Research Institute Associate Professor - School of Medicine - University of Barcelona Carrer casanova 143. Barcelona 08036. Spain Tel. (+34) 932414287 (1)
Prof. Dr. Karolien De Bosscher - Staff Scientist VIB-UGent Center for Medical Biotechnology Albert Baertsoenkaai 3 - 9000 Gent - Belgium (1)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (1)
Proteomics Facility, Netherlands Cancer Institute, Amsterdam, Netherlands. (1)

IsPrivate

False (2)

Submitter Keywords

Immuno-oncology (1)

Study type

Transcription profiling by array (155)
RNA-seq of coding RNA (22)
ChIP-seq (10)
Unknown experiment type (2)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
Transcription profiling by SAGE (1)
Human - Single-cell sequencing (1)
Cell line - One-color microarray (1)
Animal - High-throughput sequencing (1)
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Observational patient registry (1)

Release Date

2022 (453)
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2007 (26)
2006 (13)
2004 (9)
2005 (7)
2001 (3)
1999 (3)
2003 (2)
1998 (2)
2000 (1)
1997 (1)

Location

France (1)

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HIF-1synergizes with glucocorticoids to promote BFU-E progenitor self-renewal

With the aim of finding small molecules that stimulate erythropoiesis earlier than erythropoietin and that enhance CFU-E production, we studied the mechanism by which glucocorticoids increase CFU-E formation. Using BFU-E and CFU-E progenitors purified by a new technique, we demonstrate that glucocor...

ORGANISM(S): Mus musculus

2010-12-21 | E-GEOD-26086 | biostudies-arrayexpress

Metabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle

The use of glucocorticoids as growth promoters for meat-producing animals is strictly regulated within the European Union. However, in the past few years, a higher frequency of non-compliant bovine urine samples for prednisolone has been noticed, which could not be directly related to fraudulent use...

2017-01-12 | MTBLS185 | MetaboLights

Yakimchuk2019 - Mathematical modeling of immune modulation by glucocorticoids

Mathematical modeling of immune modulation by glucocorticoids Konstantin Yakimchuk https://doi.org/10.1016/j.biosystems.2019.104066 Abstract The cellular and molecular mechanisms of immunomodulatory actions of glucocorticoids (GC) remain to be identified. Using our experimental findings, a mathema...

2020-01-06 | MODEL1912170005 | BioModels

Immuno-oncology

Sexual Dimorphic Regulation of Liver Gene Expression by Glucocorticoids

Males and females exhibit differences in the incidence of many major diseases including auto-immune diseases, hepatocellular carcinoma, diabetes, and osteoporosis, which all have important inflammatory components in their etiology. Glucocorticoids are the primary physiological anti-inflammatory horm...

ORGANISM(S): Rattus norvegicus

2010-10-01 | E-GEOD-13461 | biostudies-arrayexpress

Induction of natural IgE by glucocorticoids

PRJNA841355 | ENA

Glucocorticoids and estrogen antagonism in cardiomyocytes

PRJNA600532 | ENA

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids

PRJNA1053278 | ENA

Optimizing efficacy to safety ratio of glucocorticoids in rheumatoid arthritis models by leveraging PPARα agonism

Glucocorticoids remain essential therapies for immune- and inflammatory diseases such as rheumatoid arthritis (RA) but are notorious for their metabolic side effects. Given the anti-inflammatory and metabolically favorable actions of peroxisome-proliferator activated nuclear receptor (PPAR) agonists...

ORGANISM(S): Homo sapiens (Human)

2026-09-17 | PXD084343 | Pride

Human Gw7647 Ppar Dexamethasone Glucocorticoid hormones Fibroblast-like synoviocytes

MicroRNA-146a and glucocorticoids in inflamed airway epithelial cells

PRJNA494399 | ENA

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids

PRJNA1053280 | ENA

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