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The purpose of the project was to profile protein expression liquid vitreous biopsies from uveal melanoma (UM) patients using mass spectrometry, to identify prognostic biomarkers, signaling pathways, and therapeutic targets. Vitreous biopsies were collected from two cohorts: comparative control eyes...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD043403 | Pride
Thyroid eye disease (TED) is a complex autoimmune disease that is often disfiguring and sight threatening. Recent advances have shifted the treatment paradigm from traditional immunosuppressive therapies such as corticosteroids to targeted biologic agents, such as teprotumumab (TMB; anti-IGF-1R) whi...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD066511 | Pride
The epithelium of the pulmonary airway is specially differentiated to provide defense against environmental insults, but also subject to dysregulated differentiation that results in lung disease. The current paradigm for airway epithelial differentiation is a one-step program whereby a p63+ basal ep...
ORGANISM(S): Mus musculus 
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