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MetabolomicsPostoperative Exercise Modulating Gut Microbiota and Associated Metabolites to Facilitate Bone-Tendon Healing in Rotator Cuff Tears

Background: Rotator cuff tear (RCT) is a prevalent shoulder injury, and postoperative exercise is considered to facilitate RCT healing. However, the effect of postoperative exercise on RCT healing through gut microbiota and metabolites remains unclear.

Method: The control (con) group (n=10...

2026-03-03 | MTBLS13894 | MetaboLights
ProteomicsProteomics analysis of tears and saliva from Sjogren’s syndrome patients
Sjogren’s syndrome (SS) is characterized by dysfunctional mucous membranes and dysregulated moisture-secreting glands resulting in various symptoms, including dry mouth and dry eyes. Here, we wanted to profile and compare the tears and saliva proteomes of SS patients to healthy controls. Tear and sa...
ORGANISM(S): Homo sapiens (Human) 
2021-10-04 | PXD028922 | Pride
Proteoglycan 4 Lubricin Proteomics Sjogren’s syndrome Protease Protease inhibitor Prg4 Saliva Tears 
ProteomicsProteomics characterization of extracellular vesicles sorted by flow cytometry reveals a disease-specific molecular cross-talk from cerebrospinal fluid and tears in multiple sclerosis
Several proteomics studies have been conducted to identify new cerebrospinal fluid (CSF) biomarkers in Multiple Sclerosis (MuS). However, the complexity of CSF and its invasive collection, limits its use. Therefore, the goal of biomarker research in MuS is to identify novel distinctive targets in CS...
ORGANISM(S): Homo sapiens (Human) 
2019-06-06 | PXD013794 | Pride
Proteomics  extracellular vesicles  facs sorting  csf  tears  multiple sclerosis. 
ProteomicsProteomic Analysis of Full-Thickness Rotator Cuff Tears: Potential Role of Tetranectin in Synovial Fluid
Rotator cuff tears are one of the most common shoulder disorders and can lead to pain, weakness, and limited mobility. Although the clinical condition has been widely studied, its molecular mechanisms are still not fully understood. In this study, we analyzed the proteomic profile of synovial fluid ...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD064264 | Pride
Full-thickness rotator cuff tears Synovial fluid Proteomics Tetranectin 
ProteomicsThyroid-associated orbitopathy and tears: a proteomics study
Thyroid-Associated Orbitopathy (TAO) is an autoimmune inflammatory disease that affects the eye. To date, this pathology is not very well characterised and the diagnosis remains sometimes quite challenging. The aim of this study was to try to discover in tears of TAO patients some potential biomarke...
ORGANISM(S): Homo sapiens (Human) 
2017-10-04 | PXD006871 | Pride
Lc-msms Thyroid-associated orbitopathy Human Gaz- phase fractionation Orbitrap velos pro Off-gel electrophoresis Tears Tandem mass tag 
GenomicsRNA-Seq analysis of traumatic and degenerative tears of tendon tissues of human shoulder joint
RNA-Seq analysis of traumatic and degenerative tears of tendon tissues of human shoulder joint
PRJNA749757 | ENA
GenomicsRNA-Seq analysis of traumatic and degenerative tears of subacromial bursal tissues of human shoulder joint
RNA-Seq analysis of traumatic and degenerative tears of subacromial bursal tissues of human shoulder joint
PRJNA749779 | ENA
TranscriptomicsTranscript Expression Changes over Time-from-injury in Anterior Cruciate Ligament Tears: Implications for Reconstruction and Repair
The anterior cruciate ligament (ACL) is an essential stabilizer of the tibiofemoral articulation. ACL tears often lead to functional instability and are associated with an increased risk for osteoarthritis. The healing potential of the injured ACL is poorly understood and is considered to be limited...
ORGANISM(S): Homo sapiens 
2014-09-13 | E-GEOD-61385 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of traumatic and degenerative tears of tendon tissues of human shoulder joint
Objective To identify transcript level differences between traumatic and degenerative tears of tendon tissues in shoulder joint using RNA-seq. Methods Tendon tissues were isolated from female and male patients with traumatic or degenerative tears during arthroscopic surgery (N = 31). Differentially ...
ORGANISM(S): Homo sapiens 
2022-03-15 | GSE180836 | GEO
TranscriptomicsRNA-Seq analysis of traumatic and degenerative tears of subacromial bursal tissues of human shoulder joint
Objective: To identify transcript level differences between traumatic and degenerative tears of subacromial bursal tissues in shoulder joint using RNA-seq. Methods: Bursal tissues were collected from female and male patients with traumatic or degenerative tears during arthroscopic surgery (N=32). Di...
ORGANISM(S): Homo sapiens 
2022-03-15 | GSE180857 | GEO
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