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ProteomicsINTERACTOME ANALYSIS IDENTIFIES THE ROLE OF BZW2 IN PROMOTING ENDOPLASMIC RETICULUM-MITOCHONDRIAL CONTACT AND MITOCHONDRIAL METABOLISM
Maio et. al. presents a comprehensive and quantitative interactome of BZW2, a protein found to promote human cancers with little known about its molecular function. Many of the proteins identified were either mitochondrial or endoplasmic reticulum (ER) proteins, suggesting BZW2 may play a role in mi...
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD041354 | Pride
Mercs Lipid metabolism. Mitochondrial metabolism Mam Calcium Bzw2 Interactome 
GenomicsTranscriptome profiling of colorectal cancer cells on BZW2 knockdown.
Transcriptome profiling of colorectal cancer cells on BZW2 knockdown.
PRJNA943155 | ENA
TranscriptomicsTranscriptome profiling of colorectal cancer cells on BZW2 knockdown.
Basic leucine zipper and W2 domains 2 (BZW2), also known as translation initiation regulator eIF5-mimic protein 1 (5MP1), is a member of the basic‐region leucine zipper (bZIP) superfamily of transcription factors. BZW2 has partial homology with eIF5 and can function as a competitive inhibitor of eIF...
ORGANISM(S): Homo sapiens 
2023-03-14 | GSE227069 | GEO
UnknownBZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis.
Not available
S-EPMC10329991 | biostudies-literature
UnknownBZW2/5MP1 acts as a promising target in hepatocellular carcinoma.
Not available
S-EPMC8317536 | biostudies-literature
UnknownInteractome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
Not available
S-EPMC10835002 | biostudies-literature
UnknownBZW2 promotes malignant progression in lung adenocarcinoma through enhancing the ubiquitination and degradation of GSK3β.
Not available
S-EPMC10904796 | biostudies-literature
UnknownBZW2 gene knockdown induces cell growth inhibition, G1 arrest and apoptosis in muscle-invasive bladder cancers: A microarray pathway analysis.
Not available
S-EPMC6533564 | biostudies-literature
UnknownMesenchymal stem cells-derived exosomal miR-653-5p suppresses laryngeal papilloma progression by inhibiting BZW2
Not available
S-EPMC9723928 | biostudies-literature
TranscriptomicsCRISPR RNA-seq from K562 (ENCSR528OVC)
RNA-seq on K562 cells treated with a CRISPR gRNA against BZW2. (BZW2-BGKcLV26) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2022-12-04 | GSE219360 | GEO
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