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ProteomicsA c-di-AMP receptor mediates epithelial adhesion of Lactiplantibacillus plantarum
Cyclic di-adenosine monophosphate (c-di-AMP) is a crucial second messenger used by bacteria to mediate bacterial-host interactions. However, its roles in Lactiplantibacillus plantarum remain poorly understood. Here, we identify RwpL, which consists solely of an HTH domain, as a c-di-AMP receptor in ...
ORGANISM(S): Lactobacillus plantarum WCFS1 
2026-05-25 | PXD078286 | Pride
Colonization C-di-amp Lactiplantibacillus plantarum 
ProteomicsProtemic analysis of the effect of c-di-GMP and c-di-AMP on the protein expression of Mycobacterium smegmatis
c-di-GMP and c-di-AMP are important conserved second messenger in bacteria, they play a critical role in a wide range of cellular processes, such as motility, virulence, biofilm formation, cell-cycle progression and cell development, but there are only two c-di-GMP receptors and one c-di-AMP recepto...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2019-07-03 | PXD010623 | Pride
C-di-gmp Ittaq Mycobacterium smegmatis C-di-amp 
GenomicsAllosteric regulation by c-di-AMP modulates global signal integration in Actinobacteria
Allosteric regulation by c-di-AMP modulates global signal integration in Actinobacteria
PRJNA956843 | ENA
GenomicsGene regulation by elevated c-di-AMP levels in Streptococcus pneumoniae
Gene regulation by elevated c-di-AMP levels in Streptococcus pneumoniae
PRJNA450521 | ENA
Genomicsc-di-AMP Metabolism in S. aureus
New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance in Staphylococcus aureus
PRJEB14723 | ENA
ProteomicsComparative proteomic analysis of c-di-AMP and c-di-GMP treated human gingival fibroblasts
Human gingival fibroblasts (HGFs) in the oral cavity are constantly exposed to bacteria and may or may not trigger immune responses. Lately, critical bacterial signaling molecules, cyclic-di-adenosine monophosphate (c-di-AMP) and cyclic-di-guanosine monophosphate (c-di-GMP) which play important role...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-24 | MSV000087090 | MassIVE
ProteomicsStructural basis for the c-di-AMP - dependent regulation of the stringent response by DarB
The bacterial second messenger c-di-AMP controls various cellular processes including potassium and osmolyte homeostasis. The c-di-AMP receptor protein DarB of Bacillus subtilis binds to the Rel protein and triggers the Rel-dependent stringent response. Here we report crystal structures of DarB in t...
ORGANISM(S): Bacillus subtilis subsp. subtilis 
2022-08-12 | PXD033346 | Pride
Cx-ms Bs3 Darb 
GenomicsGrowth of Staphylococcus in the absence of c-di-AMP
Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions
PRJEB22312 | ENA
GenomicsThe impact of c-di-AMP levels on gene expression in Enterococcus faecalis
The impact of c-di-AMP levels on gene expression in Enterococcus faecalis
PRJNA729656 | ENA
GenomicsAllosteric regulation by c-di-AMP modulates global signal integration in Actinobacteria
C-di-AMP is primarily associated with the regulation of carbon utilization as well as other central traits, central metabolism, and bacterial stringent response to environmental changes. Elevated c-di-AMP levels result in aberrant physiology for most c-di-AMP synthesizing organisms, drawing particul...
ORGANISM(S): Saccharopolyspora erythraea 
2024-03-31 | GSE229938 | GEO
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