Sort   by:  
 Page size 
TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
TranscriptomicsC. elegans : Control vs.Chlorpyrifos and Diazinon treatments
This SuperSeries is composed of the following subset Series: GSE16686: C. elegans : Control vs. Diazinon (1 mg/ml) treatment GSE16688: C. elegans : Control vs. Chlorpyrifos (0.5mg/ml) treatment GSE16698: C. elegans : Control vs. Chlorpyrifos (0.5mg/ml) + Diazinon (1 mg/ml) treatment Refer to individ...
ORGANISM(S): Caenorhabditis elegans 
2010-07-22 | E-GEOD-16719 | biostudies-arrayexpress
TranscriptomicsConserved nutrient sensor O-GlcNAc transferase is integral to the C. elegans pathogen-specific immune response
Discriminating pathogenic bacteria from energy-harvesting commensals is key to host immunity. Using mutants defective in the enzymes of O-linked N-acetylglucosamine (O-GlcNAc) cycling, we examined the role of this nutrient-sensing pathway in the Caenorhabidits elegans innate immune response. Using w...
ORGANISM(S): Caenorhabditis elegans 
2015-05-01 | E-GEOD-53732 | biostudies-arrayexpress
TranscriptomicsC. elegans : Control vs. Chlorpyrifos (0.5mg/ml) treatment
Transcriptional profile of C. elegans comparing control vs. nematodes treated with 0.5mg/ml of Chorpyrifos (CPF) at 16°C. Toxicant was added to agar and nematode culture on petri dishes for 72h before harvesting. One condition experiment with six biological replicates in a dye swap design.
ORGANISM(S): Caenorhabditis elegans 
2010-07-22 | E-GEOD-16688 | biostudies-arrayexpress
TranscriptomicsC. elegans : Control vs. Diazinon (1 mg/ml) treatment
Transcriptional profile of C. elegans comparing control vs. nematodes treated with 1mg/ml of Diazinon (DZN) at 16°C. Toxicant was added to agar and nematode culture on petri dishes for 72h before harvesting. One condition experiment with six biological replicates in a dye swap design.
ORGANISM(S): Caenorhabditis elegans 
2010-07-22 | E-GEOD-16686 | biostudies-arrayexpress
TranscriptomicsC. elegans nasp-1 / btr-1 mutant versus wild-type N2, exposed to pathogen Bacillus thuringiensis DB27
Transcriptional profiling of C. elegans nasp-1 / btr-1 mutant worms versus wild type N2 strain, both exposed to the bacterial pathogen Bacillus thuringiensis DB27. One-condition experiment. C. elegans nasp-1 / btr-1 mutant versus N2, exposed to Bacillus thuringiensis DB27. 3 biological replicates, i...
ORGANISM(S): Caenorhabditis elegans 
2013-01-31 | E-GEOD-43905 | biostudies-arrayexpress
TranscriptomicsC. elegans : Control vs. Chlorpyrifos (0.5mg/ml) + Diazinon (1 mg/ml) treatment
Transcriptional profile of C. elegans comparing control vs. nematodes treated with 0.5 mg/ml of Chlorpyrifos and 1mg/ml of Diazinon (DZN) at 16°C. Toxicant was added to agar and nematode culture on petri dishes for 72h before harvesting. One condition experiment with six biological replicates in a d...
ORGANISM(S): Caenorhabditis elegans 
2010-07-22 | E-GEOD-16698 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans after infection with Microbacterium nematophilum
Genomic response of C. elegans after infection with Microbacterium nematophilum.

The interaction between the nematode Caenorhabditis elegans and a Gram-positive bacterial pathogen, Microbacterium nematophilum, provides a model for an innate immune response in nematodes. This pathogen adheres ...
ORGANISM(S): Caenorhabditis elegans 
2005-01-01 | E-MEXP-696 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of LPS-stimulated RAW264.7 macrophages overexpressing Tbc1d23 novel innate immune gene
We previously identified Tbc1d23 as a candidate novel regulator of innate immunity using comparative genomics RNAi screens in C. elegans and mouse macrophages. Using mice with an engineered knockout mutation in Tbc1d23 and macrophages engineered to overexpress Tbc1d23, we now show that Tbc1d23 is a ...
ORGANISM(S): Mus musculus 
2012-04-03 | E-GEOD-30840 | biostudies-arrayexpress
TranscriptomicsExpression data from C. elegans (wild type vs. tag-24)
To provide insights into the mechanism underlying the enhanced immunity of tag-24/octr-1 animals, we used genome microarrays to find clusters of genes commonly misregulated in tag-24 relative to wild-type animals grown on live P. aeruginosa. Gravid adult wild-type and tag-24/octr-1 animals were lys...
ORGANISM(S): Caenorhabditis elegans 
2011-04-21 | E-GEOD-27867 | biostudies-arrayexpress
Sort   by:  
 Page size